Cargando…

The Impact of Neurogenic Lower Urinary Tract Symptoms and Erectile Dysfunctions on Marital Relationship in Men with Multiple Sclerosis: A Single Cohort Study

Aims: Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease that is characterized by a great variety symptoms. Most MS patients suffer from neurogenic lower urinary tract symptoms (nLUTS) and erectile dysfunctions (ED). The aim this study is to assess the impact of nLUTS and ED on m...

Descripción completa

Detalles Bibliográficos
Autores principales: Bientinesi, Riccardo, Coluzzi, Simone, Gavi, Filippo, Nociti, Viviana, Gandi, Carlo, Marino, Filippo, Moretto, Stefano, Mirabella, Massimiliano, Bassi, PierFrancesco, Sacco, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570884/
https://www.ncbi.nlm.nih.gov/pubmed/36233507
http://dx.doi.org/10.3390/jcm11195639
_version_ 1784810222168047616
author Bientinesi, Riccardo
Coluzzi, Simone
Gavi, Filippo
Nociti, Viviana
Gandi, Carlo
Marino, Filippo
Moretto, Stefano
Mirabella, Massimiliano
Bassi, PierFrancesco
Sacco, Emilio
author_facet Bientinesi, Riccardo
Coluzzi, Simone
Gavi, Filippo
Nociti, Viviana
Gandi, Carlo
Marino, Filippo
Moretto, Stefano
Mirabella, Massimiliano
Bassi, PierFrancesco
Sacco, Emilio
author_sort Bientinesi, Riccardo
collection PubMed
description Aims: Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease that is characterized by a great variety symptoms. Most MS patients suffer from neurogenic lower urinary tract symptoms (nLUTS) and erectile dysfunctions (ED). The aim this study is to assess the impact of nLUTS and ED on marital relationships in MS patients. Materials and Methods: MS male patients that arrived for our attention were prospectively enrolled in the study. All of the patients were evaluated on an Expanded Disability Status Scale (EDSS), an IIEF-5 for sexual function, an ICIQ-MLUTS for urinary function, and a Dyadic Adjustment Scale (DAS) for marital relationships. The data were analyzed using descriptive and inferential statistical tests in STATA/MP14. Results: The data of 57 male MS patients were eligible. The mean age was 45 (13.7) years, the mean disease duration was 15.49 (7.86) years, and the mean EDSS score was 3.5 (1.89). In total, 33 (57.89%) MS patients reported urine incontinence, of those, 24 (42.11%) reported UUI. The mean DAS score was 74.40 (34.58). The mean IIEF-5 score was 12.40 (8.05). The mean ICIQ-MLUTS score was 71.94 (41.06). The DAS and ICIQ-MLUTS scores were negatively correlated (r = −0.30, p < 0.001). The DAS and IIEF-5 were moderately correlated (r = 0.47, p < 0.001). The DAS and EDSS were strongly correlated (r = −0.72, p < 0.001). A univariate analysis showed that increasing age (p < 0.001), a longer disease duration (p = 0.029), a higher EDSS score (p < 0.001), and a higher ICIQ-MLUTS score (p < 0.001) were all significantly associated with lower DAS scores. Conclusions: This study demonstrated the large negative impact that nLUTS and ED due to MS have on patients’ marital relationships, highlighting the importance of a multidisciplinary approach in MS patients.
format Online
Article
Text
id pubmed-9570884
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-95708842022-10-17 The Impact of Neurogenic Lower Urinary Tract Symptoms and Erectile Dysfunctions on Marital Relationship in Men with Multiple Sclerosis: A Single Cohort Study Bientinesi, Riccardo Coluzzi, Simone Gavi, Filippo Nociti, Viviana Gandi, Carlo Marino, Filippo Moretto, Stefano Mirabella, Massimiliano Bassi, PierFrancesco Sacco, Emilio J Clin Med Article Aims: Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease that is characterized by a great variety symptoms. Most MS patients suffer from neurogenic lower urinary tract symptoms (nLUTS) and erectile dysfunctions (ED). The aim this study is to assess the impact of nLUTS and ED on marital relationships in MS patients. Materials and Methods: MS male patients that arrived for our attention were prospectively enrolled in the study. All of the patients were evaluated on an Expanded Disability Status Scale (EDSS), an IIEF-5 for sexual function, an ICIQ-MLUTS for urinary function, and a Dyadic Adjustment Scale (DAS) for marital relationships. The data were analyzed using descriptive and inferential statistical tests in STATA/MP14. Results: The data of 57 male MS patients were eligible. The mean age was 45 (13.7) years, the mean disease duration was 15.49 (7.86) years, and the mean EDSS score was 3.5 (1.89). In total, 33 (57.89%) MS patients reported urine incontinence, of those, 24 (42.11%) reported UUI. The mean DAS score was 74.40 (34.58). The mean IIEF-5 score was 12.40 (8.05). The mean ICIQ-MLUTS score was 71.94 (41.06). The DAS and ICIQ-MLUTS scores were negatively correlated (r = −0.30, p < 0.001). The DAS and IIEF-5 were moderately correlated (r = 0.47, p < 0.001). The DAS and EDSS were strongly correlated (r = −0.72, p < 0.001). A univariate analysis showed that increasing age (p < 0.001), a longer disease duration (p = 0.029), a higher EDSS score (p < 0.001), and a higher ICIQ-MLUTS score (p < 0.001) were all significantly associated with lower DAS scores. Conclusions: This study demonstrated the large negative impact that nLUTS and ED due to MS have on patients’ marital relationships, highlighting the importance of a multidisciplinary approach in MS patients. MDPI 2022-09-24 /pmc/articles/PMC9570884/ /pubmed/36233507 http://dx.doi.org/10.3390/jcm11195639 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bientinesi, Riccardo
Coluzzi, Simone
Gavi, Filippo
Nociti, Viviana
Gandi, Carlo
Marino, Filippo
Moretto, Stefano
Mirabella, Massimiliano
Bassi, PierFrancesco
Sacco, Emilio
The Impact of Neurogenic Lower Urinary Tract Symptoms and Erectile Dysfunctions on Marital Relationship in Men with Multiple Sclerosis: A Single Cohort Study
title The Impact of Neurogenic Lower Urinary Tract Symptoms and Erectile Dysfunctions on Marital Relationship in Men with Multiple Sclerosis: A Single Cohort Study
title_full The Impact of Neurogenic Lower Urinary Tract Symptoms and Erectile Dysfunctions on Marital Relationship in Men with Multiple Sclerosis: A Single Cohort Study
title_fullStr The Impact of Neurogenic Lower Urinary Tract Symptoms and Erectile Dysfunctions on Marital Relationship in Men with Multiple Sclerosis: A Single Cohort Study
title_full_unstemmed The Impact of Neurogenic Lower Urinary Tract Symptoms and Erectile Dysfunctions on Marital Relationship in Men with Multiple Sclerosis: A Single Cohort Study
title_short The Impact of Neurogenic Lower Urinary Tract Symptoms and Erectile Dysfunctions on Marital Relationship in Men with Multiple Sclerosis: A Single Cohort Study
title_sort impact of neurogenic lower urinary tract symptoms and erectile dysfunctions on marital relationship in men with multiple sclerosis: a single cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570884/
https://www.ncbi.nlm.nih.gov/pubmed/36233507
http://dx.doi.org/10.3390/jcm11195639
work_keys_str_mv AT bientinesiriccardo theimpactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT coluzzisimone theimpactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT gavifilippo theimpactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT nocitiviviana theimpactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT gandicarlo theimpactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT marinofilippo theimpactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT morettostefano theimpactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT mirabellamassimiliano theimpactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT bassipierfrancesco theimpactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT saccoemilio theimpactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT bientinesiriccardo impactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT coluzzisimone impactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT gavifilippo impactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT nocitiviviana impactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT gandicarlo impactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT marinofilippo impactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT morettostefano impactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT mirabellamassimiliano impactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT bassipierfrancesco impactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy
AT saccoemilio impactofneurogeniclowerurinarytractsymptomsanderectiledysfunctionsonmaritalrelationshipinmenwithmultiplesclerosisasinglecohortstudy