Comparing Variants of the Cell-Penetrating Peptide sC18 to Design Peptide-Drug Conjugates

Herein, the design and synthesis of peptide-drug conjugates (PDCs) including different variants of the cell-penetrating peptide sC18 is presented. We first generated a series of novel sequence mutants of sC18 having either amino acid deletions and/or substitutions, and then tested their biological a...

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Detalles Bibliográficos
Autores principales: Grabeck, Joshua, Lützenburg, Tamara, Frommelt, Pia, Neundorf, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570898/
https://www.ncbi.nlm.nih.gov/pubmed/36235193
http://dx.doi.org/10.3390/molecules27196656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570898/
https://www.ncbi.nlm.nih.gov/pubmed/36235193
http://dx.doi.org/10.3390/molecules27196656

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