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Pulmonary Embolism in the Cancer Associated Thrombosis Landscape
In cancer patients, pulmonary embolism (PE) is the second leading cause of death after the cancer itself, most likely because of difficulties in diagnosing the disease due to its nonclassical presentation. The risk of PE recurrence and possibly the case-fatality rate depends on whether the patient p...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570910/ https://www.ncbi.nlm.nih.gov/pubmed/36233519 http://dx.doi.org/10.3390/jcm11195650 |
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author | Poenou, Géraldine Dumitru Dumitru, Teona Lafaie, Ludovic Mismetti, Valentine Ayoub, Elie Duvillard, Cécile Accassat, Sandrine Mismetti, Patrick Heestermans, Marco Bertoletti, Laurent |
author_facet | Poenou, Géraldine Dumitru Dumitru, Teona Lafaie, Ludovic Mismetti, Valentine Ayoub, Elie Duvillard, Cécile Accassat, Sandrine Mismetti, Patrick Heestermans, Marco Bertoletti, Laurent |
author_sort | Poenou, Géraldine |
collection | PubMed |
description | In cancer patients, pulmonary embolism (PE) is the second leading cause of death after the cancer itself, most likely because of difficulties in diagnosing the disease due to its nonclassical presentation. The risk of PE recurrence and possibly the case-fatality rate depends on whether the patient presents a symptomatic PE, an unsuspected PE, a subsegmental PE, or a catheter-related PE. Choosing the best therapeutic option is challenging and should consider the risk of both the recurrence of thrombosis and the occurrence of bleeding. The purpose of this review is to provide an overview of the clinical characteristics and the treatment of cancer-associated PE, which could benefit clinicians to better manage the deadliest form of thrombosis associated with cancer. After a brief presentation of the epidemiological data, we will present the current attitude towards the diagnosis and the management of cancer patients with PE. Finally, we will discuss the perspectives of how the medical community can improve the management of this severe medical condition. |
format | Online Article Text |
id | pubmed-9570910 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95709102022-10-17 Pulmonary Embolism in the Cancer Associated Thrombosis Landscape Poenou, Géraldine Dumitru Dumitru, Teona Lafaie, Ludovic Mismetti, Valentine Ayoub, Elie Duvillard, Cécile Accassat, Sandrine Mismetti, Patrick Heestermans, Marco Bertoletti, Laurent J Clin Med Review In cancer patients, pulmonary embolism (PE) is the second leading cause of death after the cancer itself, most likely because of difficulties in diagnosing the disease due to its nonclassical presentation. The risk of PE recurrence and possibly the case-fatality rate depends on whether the patient presents a symptomatic PE, an unsuspected PE, a subsegmental PE, or a catheter-related PE. Choosing the best therapeutic option is challenging and should consider the risk of both the recurrence of thrombosis and the occurrence of bleeding. The purpose of this review is to provide an overview of the clinical characteristics and the treatment of cancer-associated PE, which could benefit clinicians to better manage the deadliest form of thrombosis associated with cancer. After a brief presentation of the epidemiological data, we will present the current attitude towards the diagnosis and the management of cancer patients with PE. Finally, we will discuss the perspectives of how the medical community can improve the management of this severe medical condition. MDPI 2022-09-25 /pmc/articles/PMC9570910/ /pubmed/36233519 http://dx.doi.org/10.3390/jcm11195650 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Poenou, Géraldine Dumitru Dumitru, Teona Lafaie, Ludovic Mismetti, Valentine Ayoub, Elie Duvillard, Cécile Accassat, Sandrine Mismetti, Patrick Heestermans, Marco Bertoletti, Laurent Pulmonary Embolism in the Cancer Associated Thrombosis Landscape |
title | Pulmonary Embolism in the Cancer Associated Thrombosis Landscape |
title_full | Pulmonary Embolism in the Cancer Associated Thrombosis Landscape |
title_fullStr | Pulmonary Embolism in the Cancer Associated Thrombosis Landscape |
title_full_unstemmed | Pulmonary Embolism in the Cancer Associated Thrombosis Landscape |
title_short | Pulmonary Embolism in the Cancer Associated Thrombosis Landscape |
title_sort | pulmonary embolism in the cancer associated thrombosis landscape |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570910/ https://www.ncbi.nlm.nih.gov/pubmed/36233519 http://dx.doi.org/10.3390/jcm11195650 |
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