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Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study
Background: The effect of sarcopenia on the recovery of swallowing function, and the interaction among sarcopenia, nutrition care, and rehabilitation therapy are inconclusive. Methods: This multicenter cohort study was conducted between November 2018 and October 2020 in convalescent rehabilitation h...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571320/ https://www.ncbi.nlm.nih.gov/pubmed/36235767 http://dx.doi.org/10.3390/nu14194115 |
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author | Nishioka, Shinta Fujishima, Ichiro Kishima, Masako Ohno, Tomohisa Shimizu, Akio Shigematsu, Takashi Itoda, Masataka Wakabayashi, Hidetaka Kunieda, Kenjiro Oshima, Fumiko Ogawa, Sumito Fukuma, Kazuki Ogawa, Nami Kayashita, Jun Yamada, Minoru Mori, Takashi Onizuka, Shinya |
author_facet | Nishioka, Shinta Fujishima, Ichiro Kishima, Masako Ohno, Tomohisa Shimizu, Akio Shigematsu, Takashi Itoda, Masataka Wakabayashi, Hidetaka Kunieda, Kenjiro Oshima, Fumiko Ogawa, Sumito Fukuma, Kazuki Ogawa, Nami Kayashita, Jun Yamada, Minoru Mori, Takashi Onizuka, Shinya |
author_sort | Nishioka, Shinta |
collection | PubMed |
description | Background: The effect of sarcopenia on the recovery of swallowing function, and the interaction among sarcopenia, nutrition care, and rehabilitation therapy are inconclusive. Methods: This multicenter cohort study was conducted between November 2018 and October 2020 in convalescent rehabilitation hospitals in Japan and included post-stroke patients aged ≥65 years with dysphagia. All participants were assigned to sarcopenia and non-sarcopenia groups. The primary outcome was the achievement of ≥2 Food Intake Level Scale [FILS] gain, and the secondary outcomes included Functional Independence Measure (FIM) gain and efficiency. Considering the effect modification of energy intake and rehabilitation duration, logistic regression analyses were performed. Results: Overall, 153 participants with (median age, 82 years; 57.5% women) and 40 without (median age 75 years; 35.0% women) sarcopenia were included. The non-sarcopenia group had more patients who achieved an FILS gain of ≥2 (75.0%) than the sarcopenia group (51.0%). Sarcopenia was independently associated with a poor FILS gain (odds ratio:0.34, 95% confidence intervals: 0.13–0.86) but not associated with FIM gain or efficiency. This association was not affected by the rehabilitation duration or energy intake. Conclusions: In conclusion, sarcopenia was negatively associated with the recovery of swallowing function in stroke patients without interaction by energy intake and rehabilitation duration. |
format | Online Article Text |
id | pubmed-9571320 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95713202022-10-17 Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study Nishioka, Shinta Fujishima, Ichiro Kishima, Masako Ohno, Tomohisa Shimizu, Akio Shigematsu, Takashi Itoda, Masataka Wakabayashi, Hidetaka Kunieda, Kenjiro Oshima, Fumiko Ogawa, Sumito Fukuma, Kazuki Ogawa, Nami Kayashita, Jun Yamada, Minoru Mori, Takashi Onizuka, Shinya Nutrients Article Background: The effect of sarcopenia on the recovery of swallowing function, and the interaction among sarcopenia, nutrition care, and rehabilitation therapy are inconclusive. Methods: This multicenter cohort study was conducted between November 2018 and October 2020 in convalescent rehabilitation hospitals in Japan and included post-stroke patients aged ≥65 years with dysphagia. All participants were assigned to sarcopenia and non-sarcopenia groups. The primary outcome was the achievement of ≥2 Food Intake Level Scale [FILS] gain, and the secondary outcomes included Functional Independence Measure (FIM) gain and efficiency. Considering the effect modification of energy intake and rehabilitation duration, logistic regression analyses were performed. Results: Overall, 153 participants with (median age, 82 years; 57.5% women) and 40 without (median age 75 years; 35.0% women) sarcopenia were included. The non-sarcopenia group had more patients who achieved an FILS gain of ≥2 (75.0%) than the sarcopenia group (51.0%). Sarcopenia was independently associated with a poor FILS gain (odds ratio:0.34, 95% confidence intervals: 0.13–0.86) but not associated with FIM gain or efficiency. This association was not affected by the rehabilitation duration or energy intake. Conclusions: In conclusion, sarcopenia was negatively associated with the recovery of swallowing function in stroke patients without interaction by energy intake and rehabilitation duration. MDPI 2022-10-03 /pmc/articles/PMC9571320/ /pubmed/36235767 http://dx.doi.org/10.3390/nu14194115 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Nishioka, Shinta Fujishima, Ichiro Kishima, Masako Ohno, Tomohisa Shimizu, Akio Shigematsu, Takashi Itoda, Masataka Wakabayashi, Hidetaka Kunieda, Kenjiro Oshima, Fumiko Ogawa, Sumito Fukuma, Kazuki Ogawa, Nami Kayashita, Jun Yamada, Minoru Mori, Takashi Onizuka, Shinya Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study |
title | Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study |
title_full | Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study |
title_fullStr | Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study |
title_full_unstemmed | Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study |
title_short | Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study |
title_sort | association of existence of sarcopenia and poor recovery of swallowing function in post-stroke patients with severe deglutition disorder: a multicenter cohort study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571320/ https://www.ncbi.nlm.nih.gov/pubmed/36235767 http://dx.doi.org/10.3390/nu14194115 |
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