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Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study

Background: The effect of sarcopenia on the recovery of swallowing function, and the interaction among sarcopenia, nutrition care, and rehabilitation therapy are inconclusive. Methods: This multicenter cohort study was conducted between November 2018 and October 2020 in convalescent rehabilitation h...

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Autores principales: Nishioka, Shinta, Fujishima, Ichiro, Kishima, Masako, Ohno, Tomohisa, Shimizu, Akio, Shigematsu, Takashi, Itoda, Masataka, Wakabayashi, Hidetaka, Kunieda, Kenjiro, Oshima, Fumiko, Ogawa, Sumito, Fukuma, Kazuki, Ogawa, Nami, Kayashita, Jun, Yamada, Minoru, Mori, Takashi, Onizuka, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571320/
https://www.ncbi.nlm.nih.gov/pubmed/36235767
http://dx.doi.org/10.3390/nu14194115
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author Nishioka, Shinta
Fujishima, Ichiro
Kishima, Masako
Ohno, Tomohisa
Shimizu, Akio
Shigematsu, Takashi
Itoda, Masataka
Wakabayashi, Hidetaka
Kunieda, Kenjiro
Oshima, Fumiko
Ogawa, Sumito
Fukuma, Kazuki
Ogawa, Nami
Kayashita, Jun
Yamada, Minoru
Mori, Takashi
Onizuka, Shinya
author_facet Nishioka, Shinta
Fujishima, Ichiro
Kishima, Masako
Ohno, Tomohisa
Shimizu, Akio
Shigematsu, Takashi
Itoda, Masataka
Wakabayashi, Hidetaka
Kunieda, Kenjiro
Oshima, Fumiko
Ogawa, Sumito
Fukuma, Kazuki
Ogawa, Nami
Kayashita, Jun
Yamada, Minoru
Mori, Takashi
Onizuka, Shinya
author_sort Nishioka, Shinta
collection PubMed
description Background: The effect of sarcopenia on the recovery of swallowing function, and the interaction among sarcopenia, nutrition care, and rehabilitation therapy are inconclusive. Methods: This multicenter cohort study was conducted between November 2018 and October 2020 in convalescent rehabilitation hospitals in Japan and included post-stroke patients aged ≥65 years with dysphagia. All participants were assigned to sarcopenia and non-sarcopenia groups. The primary outcome was the achievement of ≥2 Food Intake Level Scale [FILS] gain, and the secondary outcomes included Functional Independence Measure (FIM) gain and efficiency. Considering the effect modification of energy intake and rehabilitation duration, logistic regression analyses were performed. Results: Overall, 153 participants with (median age, 82 years; 57.5% women) and 40 without (median age 75 years; 35.0% women) sarcopenia were included. The non-sarcopenia group had more patients who achieved an FILS gain of ≥2 (75.0%) than the sarcopenia group (51.0%). Sarcopenia was independently associated with a poor FILS gain (odds ratio:0.34, 95% confidence intervals: 0.13–0.86) but not associated with FIM gain or efficiency. This association was not affected by the rehabilitation duration or energy intake. Conclusions: In conclusion, sarcopenia was negatively associated with the recovery of swallowing function in stroke patients without interaction by energy intake and rehabilitation duration.
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spelling pubmed-95713202022-10-17 Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study Nishioka, Shinta Fujishima, Ichiro Kishima, Masako Ohno, Tomohisa Shimizu, Akio Shigematsu, Takashi Itoda, Masataka Wakabayashi, Hidetaka Kunieda, Kenjiro Oshima, Fumiko Ogawa, Sumito Fukuma, Kazuki Ogawa, Nami Kayashita, Jun Yamada, Minoru Mori, Takashi Onizuka, Shinya Nutrients Article Background: The effect of sarcopenia on the recovery of swallowing function, and the interaction among sarcopenia, nutrition care, and rehabilitation therapy are inconclusive. Methods: This multicenter cohort study was conducted between November 2018 and October 2020 in convalescent rehabilitation hospitals in Japan and included post-stroke patients aged ≥65 years with dysphagia. All participants were assigned to sarcopenia and non-sarcopenia groups. The primary outcome was the achievement of ≥2 Food Intake Level Scale [FILS] gain, and the secondary outcomes included Functional Independence Measure (FIM) gain and efficiency. Considering the effect modification of energy intake and rehabilitation duration, logistic regression analyses were performed. Results: Overall, 153 participants with (median age, 82 years; 57.5% women) and 40 without (median age 75 years; 35.0% women) sarcopenia were included. The non-sarcopenia group had more patients who achieved an FILS gain of ≥2 (75.0%) than the sarcopenia group (51.0%). Sarcopenia was independently associated with a poor FILS gain (odds ratio:0.34, 95% confidence intervals: 0.13–0.86) but not associated with FIM gain or efficiency. This association was not affected by the rehabilitation duration or energy intake. Conclusions: In conclusion, sarcopenia was negatively associated with the recovery of swallowing function in stroke patients without interaction by energy intake and rehabilitation duration. MDPI 2022-10-03 /pmc/articles/PMC9571320/ /pubmed/36235767 http://dx.doi.org/10.3390/nu14194115 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nishioka, Shinta
Fujishima, Ichiro
Kishima, Masako
Ohno, Tomohisa
Shimizu, Akio
Shigematsu, Takashi
Itoda, Masataka
Wakabayashi, Hidetaka
Kunieda, Kenjiro
Oshima, Fumiko
Ogawa, Sumito
Fukuma, Kazuki
Ogawa, Nami
Kayashita, Jun
Yamada, Minoru
Mori, Takashi
Onizuka, Shinya
Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study
title Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study
title_full Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study
title_fullStr Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study
title_full_unstemmed Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study
title_short Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study
title_sort association of existence of sarcopenia and poor recovery of swallowing function in post-stroke patients with severe deglutition disorder: a multicenter cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571320/
https://www.ncbi.nlm.nih.gov/pubmed/36235767
http://dx.doi.org/10.3390/nu14194115
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