Cargando…
TCR CDR3 Sequencing as a Clue to Elucidate the Landscape of Dysimmunity in Patients with Primary Immune Thrombocytopenia
Background: Primary immune thrombocytopenia (ITP) is an autoimmune disorder. The existence of autoreactive T cells has long been proposed in ITP. Yet the identification of autoreactive T cells has not been achieved, which is an important step to elucidate the pathogenesis of ITP. Methods: ITP patien...
Autores principales: | Ji, Lili, Zhan, Yanxia, Wu, Boting, Chen, Pu, Cheng, Luya, Ke, Yang, Zhuang, Xibing, Hua, Fanli, Sun, Lihua, Chen, Hao, Li, Feng, Cheng, Yunfeng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571369/ https://www.ncbi.nlm.nih.gov/pubmed/36233533 http://dx.doi.org/10.3390/jcm11195665 |
Ejemplares similares
-
Proinflammatory plasticity towards Th17 paradigm of regulatory T cells consistent with elevated prevalence of TGFBR2 variants in elderly patients with primary immune thrombocytopenia
por: Cao, Jingjing, et al.
Publicado: (2023) -
Interleukin (IL)-1 family cytokines could differentiate primary immune thrombocytopenia from systemic lupus erythematosus-associated thrombocytopenia
por: Zhan, Yanxia, et al.
Publicado: (2021) -
Transcription Factor IRF4 Dysfunction Affects the Immunosuppressive Function of Treg Cells in Patients with Primary Immune Thrombocytopenia
por: Tang, Meiwen, et al.
Publicado: (2019) -
Low‐dose decitabine promotes M2 macrophage polarization in patients with primary immune thrombocytopenia via enhancing KLF4 binding to PPARγ promoter
por: Shao, Xia, et al.
Publicado: (2023) -
Circulating CX3CR1(+)CD163(+) M2 monocytes markedly elevated and correlated with cardiac markers in patients with acute myocardial infarction
por: Shao, Xia, et al.
Publicado: (2020)