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Comparative Study of Helicobacter pylori-Infected Gastritis in Okinawa and Tokyo Based on the Kyoto Classification of Gastritis

The incidence of gastric cancer in Okinawa Prefecture is the lowest in Japan, which is attributed to differences in strains of Helicobacter pylori in Okinawa and other prefectures in Japan. Our aim was to compare the endoscopic findings of H. pylori-infected gastric mucosa in Okinawa and Tokyo. Pati...

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Autores principales: Oki, Shotaro, Takeda, Tsutomu, Hojo, Mariko, Uchida, Ryota, Suzuki, Nobuyuki, Abe, Daiki, Ikeda, Atsushi, Akazawa, Yoichi, Ueyama, Hiroya, Nojiri, Shuko, Hoshino, Shinichi, Shokita, Hayashi, Nagahara, Akihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571441/
https://www.ncbi.nlm.nih.gov/pubmed/36233607
http://dx.doi.org/10.3390/jcm11195739
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author Oki, Shotaro
Takeda, Tsutomu
Hojo, Mariko
Uchida, Ryota
Suzuki, Nobuyuki
Abe, Daiki
Ikeda, Atsushi
Akazawa, Yoichi
Ueyama, Hiroya
Nojiri, Shuko
Hoshino, Shinichi
Shokita, Hayashi
Nagahara, Akihito
author_facet Oki, Shotaro
Takeda, Tsutomu
Hojo, Mariko
Uchida, Ryota
Suzuki, Nobuyuki
Abe, Daiki
Ikeda, Atsushi
Akazawa, Yoichi
Ueyama, Hiroya
Nojiri, Shuko
Hoshino, Shinichi
Shokita, Hayashi
Nagahara, Akihito
author_sort Oki, Shotaro
collection PubMed
description The incidence of gastric cancer in Okinawa Prefecture is the lowest in Japan, which is attributed to differences in strains of Helicobacter pylori in Okinawa and other prefectures in Japan. Our aim was to compare the endoscopic findings of H. pylori-infected gastric mucosa in Okinawa and Tokyo. Patients who underwent upper gastrointestinal endoscopy (UGI) at Northern Okinawa Medical Center (Okinawa group) and Juntendo University Hospital (Tokyo group) from April 2019 to March 2020 were included. Patients diagnosed with H. pylori-infected gastric mucosa were retrospectively compared between the Okinawa and Tokyo groups according to the Kyoto Classification of Gastritis. The numbers of subjects (Okinawa/Tokyo) were 435/352, male/female ratio was 247:188/181:171, and age was 53.3 ± 14.7/64.6 ± 14.3 (mean ± standard deviation) years. Regarding the Kyoto Classification of Gastritis, the prevalence (Okinawa/Tokyo) of the closed type of atrophic gastritis was 73%/37% (p < 0.001), diffuse redness 80%/84% (p = 0.145), mucosal swelling 46%/46% (p = 0.991), enlarged fold 26%/32% (p = 0.048), spotty redness 77%/68% (p = 0.002), sticky mucus 17%/36% (p < 0.001), and intestinal metaplasia 32%/42% (p < 0.001). Age analysis also revealed that closed-type atrophy and spotty redness were more frequent in the Okinawa group than in the Tokyo group. There may be regional differences in endoscopic findings of H. pylori-infected gastric mucosa between Okinawa and Tokyo.
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spelling pubmed-95714412022-10-17 Comparative Study of Helicobacter pylori-Infected Gastritis in Okinawa and Tokyo Based on the Kyoto Classification of Gastritis Oki, Shotaro Takeda, Tsutomu Hojo, Mariko Uchida, Ryota Suzuki, Nobuyuki Abe, Daiki Ikeda, Atsushi Akazawa, Yoichi Ueyama, Hiroya Nojiri, Shuko Hoshino, Shinichi Shokita, Hayashi Nagahara, Akihito J Clin Med Article The incidence of gastric cancer in Okinawa Prefecture is the lowest in Japan, which is attributed to differences in strains of Helicobacter pylori in Okinawa and other prefectures in Japan. Our aim was to compare the endoscopic findings of H. pylori-infected gastric mucosa in Okinawa and Tokyo. Patients who underwent upper gastrointestinal endoscopy (UGI) at Northern Okinawa Medical Center (Okinawa group) and Juntendo University Hospital (Tokyo group) from April 2019 to March 2020 were included. Patients diagnosed with H. pylori-infected gastric mucosa were retrospectively compared between the Okinawa and Tokyo groups according to the Kyoto Classification of Gastritis. The numbers of subjects (Okinawa/Tokyo) were 435/352, male/female ratio was 247:188/181:171, and age was 53.3 ± 14.7/64.6 ± 14.3 (mean ± standard deviation) years. Regarding the Kyoto Classification of Gastritis, the prevalence (Okinawa/Tokyo) of the closed type of atrophic gastritis was 73%/37% (p < 0.001), diffuse redness 80%/84% (p = 0.145), mucosal swelling 46%/46% (p = 0.991), enlarged fold 26%/32% (p = 0.048), spotty redness 77%/68% (p = 0.002), sticky mucus 17%/36% (p < 0.001), and intestinal metaplasia 32%/42% (p < 0.001). Age analysis also revealed that closed-type atrophy and spotty redness were more frequent in the Okinawa group than in the Tokyo group. There may be regional differences in endoscopic findings of H. pylori-infected gastric mucosa between Okinawa and Tokyo. MDPI 2022-09-28 /pmc/articles/PMC9571441/ /pubmed/36233607 http://dx.doi.org/10.3390/jcm11195739 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Oki, Shotaro
Takeda, Tsutomu
Hojo, Mariko
Uchida, Ryota
Suzuki, Nobuyuki
Abe, Daiki
Ikeda, Atsushi
Akazawa, Yoichi
Ueyama, Hiroya
Nojiri, Shuko
Hoshino, Shinichi
Shokita, Hayashi
Nagahara, Akihito
Comparative Study of Helicobacter pylori-Infected Gastritis in Okinawa and Tokyo Based on the Kyoto Classification of Gastritis
title Comparative Study of Helicobacter pylori-Infected Gastritis in Okinawa and Tokyo Based on the Kyoto Classification of Gastritis
title_full Comparative Study of Helicobacter pylori-Infected Gastritis in Okinawa and Tokyo Based on the Kyoto Classification of Gastritis
title_fullStr Comparative Study of Helicobacter pylori-Infected Gastritis in Okinawa and Tokyo Based on the Kyoto Classification of Gastritis
title_full_unstemmed Comparative Study of Helicobacter pylori-Infected Gastritis in Okinawa and Tokyo Based on the Kyoto Classification of Gastritis
title_short Comparative Study of Helicobacter pylori-Infected Gastritis in Okinawa and Tokyo Based on the Kyoto Classification of Gastritis
title_sort comparative study of helicobacter pylori-infected gastritis in okinawa and tokyo based on the kyoto classification of gastritis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571441/
https://www.ncbi.nlm.nih.gov/pubmed/36233607
http://dx.doi.org/10.3390/jcm11195739
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