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Development of UPLC-MS/MS Method to Study the Pharmacokinetic Interaction between Sorafenib and Dapagliflozin in Rats

Sorafenib (SOR), an inhibitor of multiple kinases, is a classic targeted drug for advanced hepatocellular carcinoma (HCC) which often coexists with type 2 diabetes mellitus (T2DM). Dapagliflozin (DAPA), a sodium–glucose cotransporter-2 inhibitor (SGLT2i), is widely used in patients with T2DM. Notabl...

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Detalles Bibliográficos
Autores principales:	He, Xueru, Li, Ying, Ma, Yinling, Fu, Yuhao, Xun, Xuejiao, Cui, Yanjun, Dong, Zhanjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571628/ https://www.ncbi.nlm.nih.gov/pubmed/36234746 http://dx.doi.org/10.3390/molecules27196190

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