Monotropein Protects against Inflammatory Bone Loss and Suppresses Osteoclast Formation and Bone Resorption by Inhibiting NFATc1 via NF-κB and Akt/GSK-3β Pathway

Monotropein (Mon) is a kind of iridoid glycoside plant secondary metabolite primarily present in some edible and medicinal plants. The aim of this study was to investigate the effect of Mon on lipopolysaccharide (LPS)-induced inflammatory bone loss in mice and osteoclasts (OCs) derived from bone mar...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Qi, Hu, Sijing, He, Yuqiong, Song, Zile, Shen, Yi, Zhao, Zihui, Zhang, Quanlong, Qin, Luping, Zhang, Qiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571677/
https://www.ncbi.nlm.nih.gov/pubmed/36235631
http://dx.doi.org/10.3390/nu14193978