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Trimethylamine, a gut bacteria metabolite and air pollutant, increases blood pressure and markers of kidney damage including proteinuria and KIM-1 in rats
BACKGROUND: Trimethylamine oxide (TMAO) is a biomarker in cardiovascular and renal diseases. TMAO originates from the oxidation of trimethylamine (TMA), a product of gut microbiota and manufacturing industries-derived pollutant, by flavin monooxygenases (FMOs). The effect of chronic exposure to TMA...
Autores principales: | Maksymiuk, Klaudia M., Szudzik, Mateusz, Gawryś-Kopczyńska, Marta, Onyszkiewicz, Maksymilian, Samborowska, Emilia, Mogilnicka, Izabella, Ufnal, Marcin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571686/ https://www.ncbi.nlm.nih.gov/pubmed/36243862 http://dx.doi.org/10.1186/s12967-022-03687-y |
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