Cargando…

Combined Trans-Arterial Embolization and Ablation for the Treatment of Large (>3 cm) Liver Metastases: Review of the Literature

(1) Background: The aim of this review was to determine the state of clinical practice in the role of the combined approach of embolization and ablation in patients with secondary liver lesions greater than 3 cm who are not candidates for surgery, and to study its safety and efficacy. (2) Methods: T...

Descripción completa

Detalles Bibliográficos
Autores principales: Faiella, Eliodoro, Calabrese, Alessandro, Santucci, Domiziana, de Felice, Carlo, Pusceddu, Claudio, Fior, Davide, Fontana, Federico, Piacentino, Filippo, Moramarco, Lorenzo Paolo, Muraca, Rosa Maria, Venturini, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571710/
https://www.ncbi.nlm.nih.gov/pubmed/36233437
http://dx.doi.org/10.3390/jcm11195576
_version_ 1784810430190845952
author Faiella, Eliodoro
Calabrese, Alessandro
Santucci, Domiziana
de Felice, Carlo
Pusceddu, Claudio
Fior, Davide
Fontana, Federico
Piacentino, Filippo
Moramarco, Lorenzo Paolo
Muraca, Rosa Maria
Venturini, Massimo
author_facet Faiella, Eliodoro
Calabrese, Alessandro
Santucci, Domiziana
de Felice, Carlo
Pusceddu, Claudio
Fior, Davide
Fontana, Federico
Piacentino, Filippo
Moramarco, Lorenzo Paolo
Muraca, Rosa Maria
Venturini, Massimo
author_sort Faiella, Eliodoro
collection PubMed
description (1) Background: The aim of this review was to determine the state of clinical practice in the role of the combined approach of embolization and ablation in patients with secondary liver lesions greater than 3 cm who are not candidates for surgery, and to study its safety and efficacy. (2) Methods: Two reviewers conducted the literature search independently. Eight articles on the combined approach of embolization and ablation in secondary liver lesions were selected. (3) Results: The studies were published between 2009 and 2020. Two studies were prospective in design. The sample size was < 100 patients for all studies. All studies demonstrated the safety of the combined approach based on the low complication rate. Some studies lamented non-uniform systemic chemotherapy regimens and the variability in the sequence of embolization and ablation. (4) Conclusions: This review presents the combined approach of ablation and embolization in liver lesions greater than 3 cm as a safe therapeutic procedure with positive effects on patient survival. Prospective and multicentric studies are needed to further evaluate its efficacy.
format Online
Article
Text
id pubmed-9571710
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-95717102022-10-17 Combined Trans-Arterial Embolization and Ablation for the Treatment of Large (>3 cm) Liver Metastases: Review of the Literature Faiella, Eliodoro Calabrese, Alessandro Santucci, Domiziana de Felice, Carlo Pusceddu, Claudio Fior, Davide Fontana, Federico Piacentino, Filippo Moramarco, Lorenzo Paolo Muraca, Rosa Maria Venturini, Massimo J Clin Med Review (1) Background: The aim of this review was to determine the state of clinical practice in the role of the combined approach of embolization and ablation in patients with secondary liver lesions greater than 3 cm who are not candidates for surgery, and to study its safety and efficacy. (2) Methods: Two reviewers conducted the literature search independently. Eight articles on the combined approach of embolization and ablation in secondary liver lesions were selected. (3) Results: The studies were published between 2009 and 2020. Two studies were prospective in design. The sample size was < 100 patients for all studies. All studies demonstrated the safety of the combined approach based on the low complication rate. Some studies lamented non-uniform systemic chemotherapy regimens and the variability in the sequence of embolization and ablation. (4) Conclusions: This review presents the combined approach of ablation and embolization in liver lesions greater than 3 cm as a safe therapeutic procedure with positive effects on patient survival. Prospective and multicentric studies are needed to further evaluate its efficacy. MDPI 2022-09-22 /pmc/articles/PMC9571710/ /pubmed/36233437 http://dx.doi.org/10.3390/jcm11195576 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Faiella, Eliodoro
Calabrese, Alessandro
Santucci, Domiziana
de Felice, Carlo
Pusceddu, Claudio
Fior, Davide
Fontana, Federico
Piacentino, Filippo
Moramarco, Lorenzo Paolo
Muraca, Rosa Maria
Venturini, Massimo
Combined Trans-Arterial Embolization and Ablation for the Treatment of Large (>3 cm) Liver Metastases: Review of the Literature
title Combined Trans-Arterial Embolization and Ablation for the Treatment of Large (>3 cm) Liver Metastases: Review of the Literature
title_full Combined Trans-Arterial Embolization and Ablation for the Treatment of Large (>3 cm) Liver Metastases: Review of the Literature
title_fullStr Combined Trans-Arterial Embolization and Ablation for the Treatment of Large (>3 cm) Liver Metastases: Review of the Literature
title_full_unstemmed Combined Trans-Arterial Embolization and Ablation for the Treatment of Large (>3 cm) Liver Metastases: Review of the Literature
title_short Combined Trans-Arterial Embolization and Ablation for the Treatment of Large (>3 cm) Liver Metastases: Review of the Literature
title_sort combined trans-arterial embolization and ablation for the treatment of large (>3 cm) liver metastases: review of the literature
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571710/
https://www.ncbi.nlm.nih.gov/pubmed/36233437
http://dx.doi.org/10.3390/jcm11195576
work_keys_str_mv AT faiellaeliodoro combinedtransarterialembolizationandablationforthetreatmentoflarge3cmlivermetastasesreviewoftheliterature
AT calabresealessandro combinedtransarterialembolizationandablationforthetreatmentoflarge3cmlivermetastasesreviewoftheliterature
AT santuccidomiziana combinedtransarterialembolizationandablationforthetreatmentoflarge3cmlivermetastasesreviewoftheliterature
AT defelicecarlo combinedtransarterialembolizationandablationforthetreatmentoflarge3cmlivermetastasesreviewoftheliterature
AT puscedduclaudio combinedtransarterialembolizationandablationforthetreatmentoflarge3cmlivermetastasesreviewoftheliterature
AT fiordavide combinedtransarterialembolizationandablationforthetreatmentoflarge3cmlivermetastasesreviewoftheliterature
AT fontanafederico combinedtransarterialembolizationandablationforthetreatmentoflarge3cmlivermetastasesreviewoftheliterature
AT piacentinofilippo combinedtransarterialembolizationandablationforthetreatmentoflarge3cmlivermetastasesreviewoftheliterature
AT moramarcolorenzopaolo combinedtransarterialembolizationandablationforthetreatmentoflarge3cmlivermetastasesreviewoftheliterature
AT muracarosamaria combinedtransarterialembolizationandablationforthetreatmentoflarge3cmlivermetastasesreviewoftheliterature
AT venturinimassimo combinedtransarterialembolizationandablationforthetreatmentoflarge3cmlivermetastasesreviewoftheliterature