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Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain

The aims of this study are: (1) to determine cause-specific survival by stage, grade, and molecular groups of breast cancer, (2) to identify factors which explain and predict the likelihood of survival and the risk of dying from this cancer; and (3) to find out the distribution of breast cancer case...

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Autores principales: Pascual, Maria Clara, Montaño, Juan José, Franch, Paula, Sánchez-Contador, Carmen, Ramos, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571737/
https://www.ncbi.nlm.nih.gov/pubmed/36233576
http://dx.doi.org/10.3390/jcm11195708
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author Pascual, Maria Clara
Montaño, Juan José
Franch, Paula
Sánchez-Contador, Carmen
Ramos, Maria
author_facet Pascual, Maria Clara
Montaño, Juan José
Franch, Paula
Sánchez-Contador, Carmen
Ramos, Maria
author_sort Pascual, Maria Clara
collection PubMed
description The aims of this study are: (1) to determine cause-specific survival by stage, grade, and molecular groups of breast cancer, (2) to identify factors which explain and predict the likelihood of survival and the risk of dying from this cancer; and (3) to find out the distribution of breast cancer cases by stage, grade, and molecular groups in females diagnosed in the period 2006–2012 in Mallorca (Spain). We collected data regarding age, date and diagnostic method, histology, laterality, sublocation, pathological or clinical tumor size (T), pathological or clinical regional lymph nodes (N), metastasis (M) and stage, histologic grade, estrogen and progesterone receptors status, HER-2 expression, Ki67 level, molecular classification, date of last follow-up or date of death, and cause of death. We identified 2869 cases. Cause-specific survival for the entire sample was 96% 1 year after diagnosis, 91% at 3 years and 87% at 5 years. Relative survival was 96.9% 1 year after diagnosis, 92.6% at 3 years and 88.5% at 5 years. The competing-risks regression model determined that patients over 65 years of age and patients with triple negative cancer have worse prognoses, and as stages progress, the prognosis for breast cancer worsens, especially from stage III.
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spelling pubmed-95717372022-10-17 Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain Pascual, Maria Clara Montaño, Juan José Franch, Paula Sánchez-Contador, Carmen Ramos, Maria J Clin Med Article The aims of this study are: (1) to determine cause-specific survival by stage, grade, and molecular groups of breast cancer, (2) to identify factors which explain and predict the likelihood of survival and the risk of dying from this cancer; and (3) to find out the distribution of breast cancer cases by stage, grade, and molecular groups in females diagnosed in the period 2006–2012 in Mallorca (Spain). We collected data regarding age, date and diagnostic method, histology, laterality, sublocation, pathological or clinical tumor size (T), pathological or clinical regional lymph nodes (N), metastasis (M) and stage, histologic grade, estrogen and progesterone receptors status, HER-2 expression, Ki67 level, molecular classification, date of last follow-up or date of death, and cause of death. We identified 2869 cases. Cause-specific survival for the entire sample was 96% 1 year after diagnosis, 91% at 3 years and 87% at 5 years. Relative survival was 96.9% 1 year after diagnosis, 92.6% at 3 years and 88.5% at 5 years. The competing-risks regression model determined that patients over 65 years of age and patients with triple negative cancer have worse prognoses, and as stages progress, the prognosis for breast cancer worsens, especially from stage III. MDPI 2022-09-27 /pmc/articles/PMC9571737/ /pubmed/36233576 http://dx.doi.org/10.3390/jcm11195708 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pascual, Maria Clara
Montaño, Juan José
Franch, Paula
Sánchez-Contador, Carmen
Ramos, Maria
Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain
title Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain
title_full Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain
title_fullStr Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain
title_full_unstemmed Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain
title_short Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain
title_sort survival of breast cancer by stage, grade and molecular groups in mallorca, spain
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571737/
https://www.ncbi.nlm.nih.gov/pubmed/36233576
http://dx.doi.org/10.3390/jcm11195708
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