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Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain
The aims of this study are: (1) to determine cause-specific survival by stage, grade, and molecular groups of breast cancer, (2) to identify factors which explain and predict the likelihood of survival and the risk of dying from this cancer; and (3) to find out the distribution of breast cancer case...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571737/ https://www.ncbi.nlm.nih.gov/pubmed/36233576 http://dx.doi.org/10.3390/jcm11195708 |
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author | Pascual, Maria Clara Montaño, Juan José Franch, Paula Sánchez-Contador, Carmen Ramos, Maria |
author_facet | Pascual, Maria Clara Montaño, Juan José Franch, Paula Sánchez-Contador, Carmen Ramos, Maria |
author_sort | Pascual, Maria Clara |
collection | PubMed |
description | The aims of this study are: (1) to determine cause-specific survival by stage, grade, and molecular groups of breast cancer, (2) to identify factors which explain and predict the likelihood of survival and the risk of dying from this cancer; and (3) to find out the distribution of breast cancer cases by stage, grade, and molecular groups in females diagnosed in the period 2006–2012 in Mallorca (Spain). We collected data regarding age, date and diagnostic method, histology, laterality, sublocation, pathological or clinical tumor size (T), pathological or clinical regional lymph nodes (N), metastasis (M) and stage, histologic grade, estrogen and progesterone receptors status, HER-2 expression, Ki67 level, molecular classification, date of last follow-up or date of death, and cause of death. We identified 2869 cases. Cause-specific survival for the entire sample was 96% 1 year after diagnosis, 91% at 3 years and 87% at 5 years. Relative survival was 96.9% 1 year after diagnosis, 92.6% at 3 years and 88.5% at 5 years. The competing-risks regression model determined that patients over 65 years of age and patients with triple negative cancer have worse prognoses, and as stages progress, the prognosis for breast cancer worsens, especially from stage III. |
format | Online Article Text |
id | pubmed-9571737 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95717372022-10-17 Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain Pascual, Maria Clara Montaño, Juan José Franch, Paula Sánchez-Contador, Carmen Ramos, Maria J Clin Med Article The aims of this study are: (1) to determine cause-specific survival by stage, grade, and molecular groups of breast cancer, (2) to identify factors which explain and predict the likelihood of survival and the risk of dying from this cancer; and (3) to find out the distribution of breast cancer cases by stage, grade, and molecular groups in females diagnosed in the period 2006–2012 in Mallorca (Spain). We collected data regarding age, date and diagnostic method, histology, laterality, sublocation, pathological or clinical tumor size (T), pathological or clinical regional lymph nodes (N), metastasis (M) and stage, histologic grade, estrogen and progesterone receptors status, HER-2 expression, Ki67 level, molecular classification, date of last follow-up or date of death, and cause of death. We identified 2869 cases. Cause-specific survival for the entire sample was 96% 1 year after diagnosis, 91% at 3 years and 87% at 5 years. Relative survival was 96.9% 1 year after diagnosis, 92.6% at 3 years and 88.5% at 5 years. The competing-risks regression model determined that patients over 65 years of age and patients with triple negative cancer have worse prognoses, and as stages progress, the prognosis for breast cancer worsens, especially from stage III. MDPI 2022-09-27 /pmc/articles/PMC9571737/ /pubmed/36233576 http://dx.doi.org/10.3390/jcm11195708 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Pascual, Maria Clara Montaño, Juan José Franch, Paula Sánchez-Contador, Carmen Ramos, Maria Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain |
title | Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain |
title_full | Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain |
title_fullStr | Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain |
title_full_unstemmed | Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain |
title_short | Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain |
title_sort | survival of breast cancer by stage, grade and molecular groups in mallorca, spain |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571737/ https://www.ncbi.nlm.nih.gov/pubmed/36233576 http://dx.doi.org/10.3390/jcm11195708 |
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