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The Role of Vascular Risk Factors in Post-Stroke Delirium: A Systematic Review and Meta-Analysis

Vascular risk factors may predispose to post-stroke delirium (PSD). A systematic review and meta-analysis were performed by searching PubMed, Web of Science, and Scopus. The primary outcome was the prevalence of vascular risk factors in PSD vs. non-PSD patients. Odds ratios (ORs) with 95% confidence...

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Autores principales: Siokas, Vasileios, Fleischmann, Robert, Feil, Katharina, Liampas, Ioannis, Kowarik, Markus C., Bai, Yang, Stefanou, Maria-Ioanna, Poli, Sven, Ziemann, Ulf, Dardiotis, Efthimios, Mengel, Annerose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571874/
https://www.ncbi.nlm.nih.gov/pubmed/36233701
http://dx.doi.org/10.3390/jcm11195835
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author Siokas, Vasileios
Fleischmann, Robert
Feil, Katharina
Liampas, Ioannis
Kowarik, Markus C.
Bai, Yang
Stefanou, Maria-Ioanna
Poli, Sven
Ziemann, Ulf
Dardiotis, Efthimios
Mengel, Annerose
author_facet Siokas, Vasileios
Fleischmann, Robert
Feil, Katharina
Liampas, Ioannis
Kowarik, Markus C.
Bai, Yang
Stefanou, Maria-Ioanna
Poli, Sven
Ziemann, Ulf
Dardiotis, Efthimios
Mengel, Annerose
author_sort Siokas, Vasileios
collection PubMed
description Vascular risk factors may predispose to post-stroke delirium (PSD). A systematic review and meta-analysis were performed by searching PubMed, Web of Science, and Scopus. The primary outcome was the prevalence of vascular risk factors in PSD vs. non-PSD patients. Odds ratios (ORs) with 95% confidence intervals (CIs) and mean differences (MDs) with 95% CIs were calculated for categorical and continuous variables, respectively. Fixed effects or random effects models were used in case of low- or high-statistical heterogeneity, respectively. We found an increased prevalence of atrial fibrillation (OR = 1.74, p = 0.0004), prior stroke (OR = 1.48, p < 0.00001), coronary artery disease (OR = 1.48, p < 0.00001), heart failure (OR = 2.01, p < 0.0001), and peripheral vascular disease (OR = 2.03, p < 0.00001) in patients with vs. without PSD. PSD patients were older (MD = 5.27 y, p < 0.00001) compared with their non-PSD counterparts. Advanced age, atrial fibrillation, prior stroke, coronary artery disease, heart failure, and peripheral vascular disease appeared to be significantly associated with PSD.
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spelling pubmed-95718742022-10-17 The Role of Vascular Risk Factors in Post-Stroke Delirium: A Systematic Review and Meta-Analysis Siokas, Vasileios Fleischmann, Robert Feil, Katharina Liampas, Ioannis Kowarik, Markus C. Bai, Yang Stefanou, Maria-Ioanna Poli, Sven Ziemann, Ulf Dardiotis, Efthimios Mengel, Annerose J Clin Med Review Vascular risk factors may predispose to post-stroke delirium (PSD). A systematic review and meta-analysis were performed by searching PubMed, Web of Science, and Scopus. The primary outcome was the prevalence of vascular risk factors in PSD vs. non-PSD patients. Odds ratios (ORs) with 95% confidence intervals (CIs) and mean differences (MDs) with 95% CIs were calculated for categorical and continuous variables, respectively. Fixed effects or random effects models were used in case of low- or high-statistical heterogeneity, respectively. We found an increased prevalence of atrial fibrillation (OR = 1.74, p = 0.0004), prior stroke (OR = 1.48, p < 0.00001), coronary artery disease (OR = 1.48, p < 0.00001), heart failure (OR = 2.01, p < 0.0001), and peripheral vascular disease (OR = 2.03, p < 0.00001) in patients with vs. without PSD. PSD patients were older (MD = 5.27 y, p < 0.00001) compared with their non-PSD counterparts. Advanced age, atrial fibrillation, prior stroke, coronary artery disease, heart failure, and peripheral vascular disease appeared to be significantly associated with PSD. MDPI 2022-10-01 /pmc/articles/PMC9571874/ /pubmed/36233701 http://dx.doi.org/10.3390/jcm11195835 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Siokas, Vasileios
Fleischmann, Robert
Feil, Katharina
Liampas, Ioannis
Kowarik, Markus C.
Bai, Yang
Stefanou, Maria-Ioanna
Poli, Sven
Ziemann, Ulf
Dardiotis, Efthimios
Mengel, Annerose
The Role of Vascular Risk Factors in Post-Stroke Delirium: A Systematic Review and Meta-Analysis
title The Role of Vascular Risk Factors in Post-Stroke Delirium: A Systematic Review and Meta-Analysis
title_full The Role of Vascular Risk Factors in Post-Stroke Delirium: A Systematic Review and Meta-Analysis
title_fullStr The Role of Vascular Risk Factors in Post-Stroke Delirium: A Systematic Review and Meta-Analysis
title_full_unstemmed The Role of Vascular Risk Factors in Post-Stroke Delirium: A Systematic Review and Meta-Analysis
title_short The Role of Vascular Risk Factors in Post-Stroke Delirium: A Systematic Review and Meta-Analysis
title_sort role of vascular risk factors in post-stroke delirium: a systematic review and meta-analysis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571874/
https://www.ncbi.nlm.nih.gov/pubmed/36233701
http://dx.doi.org/10.3390/jcm11195835
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