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MINOCA: One Size Fits All? Probably Not—A Review of Etiology, Investigation, and Treatment

Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a heterogeneous group of conditions that include both atherosclerotic (coronary plaque disruption) and non-atherosclerotic (spontaneous coronary artery dissection, coronary artery spasm, coronary artery embolism, coronary micro...

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Autores principales: Herling de Oliveira, Lucas Lentini, Correia, Vinícius Machado, Nicz, Pedro Felipe Gomes, Soares, Paulo Rogério, Scudeler, Thiago Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571924/
https://www.ncbi.nlm.nih.gov/pubmed/36233366
http://dx.doi.org/10.3390/jcm11195497
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author Herling de Oliveira, Lucas Lentini
Correia, Vinícius Machado
Nicz, Pedro Felipe Gomes
Soares, Paulo Rogério
Scudeler, Thiago Luis
author_facet Herling de Oliveira, Lucas Lentini
Correia, Vinícius Machado
Nicz, Pedro Felipe Gomes
Soares, Paulo Rogério
Scudeler, Thiago Luis
author_sort Herling de Oliveira, Lucas Lentini
collection PubMed
description Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a heterogeneous group of conditions that include both atherosclerotic (coronary plaque disruption) and non-atherosclerotic (spontaneous coronary artery dissection, coronary artery spasm, coronary artery embolism, coronary microvascular dysfunction, and supply–demand mismatch) causes resulting in myocardial damage that is not due to obstructive coronary artery disease. Failure to identify the underlying cause may result in inadequate and inappropriate therapy in these patients. The cornerstone of managing MINOCA patients is to identify the underlying mechanism to achieve the target treatment. Intravascular imaging is able to identify different morphologic features of coronary plaques, while cardiac magnetic resonance is the gold standard for detection of myocardial infarction in the setting of MINOCA. In this review, we summarize the relevant clinical issues, contemporary diagnosis, and treatment options of MINOCA.
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spelling pubmed-95719242022-10-17 MINOCA: One Size Fits All? Probably Not—A Review of Etiology, Investigation, and Treatment Herling de Oliveira, Lucas Lentini Correia, Vinícius Machado Nicz, Pedro Felipe Gomes Soares, Paulo Rogério Scudeler, Thiago Luis J Clin Med Review Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a heterogeneous group of conditions that include both atherosclerotic (coronary plaque disruption) and non-atherosclerotic (spontaneous coronary artery dissection, coronary artery spasm, coronary artery embolism, coronary microvascular dysfunction, and supply–demand mismatch) causes resulting in myocardial damage that is not due to obstructive coronary artery disease. Failure to identify the underlying cause may result in inadequate and inappropriate therapy in these patients. The cornerstone of managing MINOCA patients is to identify the underlying mechanism to achieve the target treatment. Intravascular imaging is able to identify different morphologic features of coronary plaques, while cardiac magnetic resonance is the gold standard for detection of myocardial infarction in the setting of MINOCA. In this review, we summarize the relevant clinical issues, contemporary diagnosis, and treatment options of MINOCA. MDPI 2022-09-20 /pmc/articles/PMC9571924/ /pubmed/36233366 http://dx.doi.org/10.3390/jcm11195497 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Herling de Oliveira, Lucas Lentini
Correia, Vinícius Machado
Nicz, Pedro Felipe Gomes
Soares, Paulo Rogério
Scudeler, Thiago Luis
MINOCA: One Size Fits All? Probably Not—A Review of Etiology, Investigation, and Treatment
title MINOCA: One Size Fits All? Probably Not—A Review of Etiology, Investigation, and Treatment
title_full MINOCA: One Size Fits All? Probably Not—A Review of Etiology, Investigation, and Treatment
title_fullStr MINOCA: One Size Fits All? Probably Not—A Review of Etiology, Investigation, and Treatment
title_full_unstemmed MINOCA: One Size Fits All? Probably Not—A Review of Etiology, Investigation, and Treatment
title_short MINOCA: One Size Fits All? Probably Not—A Review of Etiology, Investigation, and Treatment
title_sort minoca: one size fits all? probably not—a review of etiology, investigation, and treatment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571924/
https://www.ncbi.nlm.nih.gov/pubmed/36233366
http://dx.doi.org/10.3390/jcm11195497
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