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Homology Modeling, Molecular Docking, Molecular Dynamic Simulation, and Drug-Likeness of the Modified Alpha-Mangostin against the β-Tubulin Protein of Acanthamoeba Keratitis

Acanthamoeba species are capable of causing amoebic keratitis (AK). As a monotherapy, alpha-mangostin is effective for the treatment of AK; however, its bioavailability is quite poor. Moreover, the efficacy of therapy is contingent on the parasite and virulent strains. To improve readiness against A...

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Detalles Bibliográficos
Autores principales:	Ongtanasup, Tassanee, Mazumder, Anisha, Dwivedi, Anupma, Eawsakul, Komgrit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572066/ https://www.ncbi.nlm.nih.gov/pubmed/36234875 http://dx.doi.org/10.3390/molecules27196338

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