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Functional Outcomes after Selective Clamping in Robot-Assisted Partial Nephrectomy

This study aimed to assess the risks and benefits of selective clamping in robot-assisted partial nephrectomy (RAPN). We retrospectively analyzed 372 patients who had undergone RAPN at our hospital between July 2010 and March 2021. After propensity score matching between the full and selective clamp...

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Autores principales: Takahara, Kiyoshi, Kusaka, Mamoru, Nukaya, Takuhisa, Takenaka, Masashi, Zennami, Kenji, Ichino, Manabu, Sasaki, Hitomi, Sumitomo, Makoto, Shiroki, Ryoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572118/
https://www.ncbi.nlm.nih.gov/pubmed/36233518
http://dx.doi.org/10.3390/jcm11195648
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author Takahara, Kiyoshi
Kusaka, Mamoru
Nukaya, Takuhisa
Takenaka, Masashi
Zennami, Kenji
Ichino, Manabu
Sasaki, Hitomi
Sumitomo, Makoto
Shiroki, Ryoichi
author_facet Takahara, Kiyoshi
Kusaka, Mamoru
Nukaya, Takuhisa
Takenaka, Masashi
Zennami, Kenji
Ichino, Manabu
Sasaki, Hitomi
Sumitomo, Makoto
Shiroki, Ryoichi
author_sort Takahara, Kiyoshi
collection PubMed
description This study aimed to assess the risks and benefits of selective clamping in robot-assisted partial nephrectomy (RAPN). We retrospectively analyzed 372 patients who had undergone RAPN at our hospital between July 2010 and March 2021. After propensity score matching between the full and selective clamping groups, perioperative outcomes and postoperative preservation ratio of the estimated glomerular filtration rate (eGFR) were compared at 6 and 12 months of follow-up. After propensity score matching, we evaluated 47 patients from each group. While no significant differences were observed in surgical time, warm ischemia time, or incidence rates of all grades of complications between the two cohorts, the estimated blood loss (EBL) was significantly lower in the full clamping group than in the selective clamping group (30 vs. 60, p = 0.046). However, no significant intergroup differences were observed in the postoperative preservation ratio of eGFR at 6 or 12 months of follow-up (full clamping 94.0% vs. selective clamping 92.7%, p = 0.509, and full clamping 92.0% vs. selective clamping 91.6%, p = 0.476, respectively). Selective clamping resulted in higher EBL rates than did full clamping in RAPN. However, selective clamping provided no renal functional advantage over full clamping in our propensity-score-matched cohort.
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spelling pubmed-95721182022-10-17 Functional Outcomes after Selective Clamping in Robot-Assisted Partial Nephrectomy Takahara, Kiyoshi Kusaka, Mamoru Nukaya, Takuhisa Takenaka, Masashi Zennami, Kenji Ichino, Manabu Sasaki, Hitomi Sumitomo, Makoto Shiroki, Ryoichi J Clin Med Article This study aimed to assess the risks and benefits of selective clamping in robot-assisted partial nephrectomy (RAPN). We retrospectively analyzed 372 patients who had undergone RAPN at our hospital between July 2010 and March 2021. After propensity score matching between the full and selective clamping groups, perioperative outcomes and postoperative preservation ratio of the estimated glomerular filtration rate (eGFR) were compared at 6 and 12 months of follow-up. After propensity score matching, we evaluated 47 patients from each group. While no significant differences were observed in surgical time, warm ischemia time, or incidence rates of all grades of complications between the two cohorts, the estimated blood loss (EBL) was significantly lower in the full clamping group than in the selective clamping group (30 vs. 60, p = 0.046). However, no significant intergroup differences were observed in the postoperative preservation ratio of eGFR at 6 or 12 months of follow-up (full clamping 94.0% vs. selective clamping 92.7%, p = 0.509, and full clamping 92.0% vs. selective clamping 91.6%, p = 0.476, respectively). Selective clamping resulted in higher EBL rates than did full clamping in RAPN. However, selective clamping provided no renal functional advantage over full clamping in our propensity-score-matched cohort. MDPI 2022-09-25 /pmc/articles/PMC9572118/ /pubmed/36233518 http://dx.doi.org/10.3390/jcm11195648 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Takahara, Kiyoshi
Kusaka, Mamoru
Nukaya, Takuhisa
Takenaka, Masashi
Zennami, Kenji
Ichino, Manabu
Sasaki, Hitomi
Sumitomo, Makoto
Shiroki, Ryoichi
Functional Outcomes after Selective Clamping in Robot-Assisted Partial Nephrectomy
title Functional Outcomes after Selective Clamping in Robot-Assisted Partial Nephrectomy
title_full Functional Outcomes after Selective Clamping in Robot-Assisted Partial Nephrectomy
title_fullStr Functional Outcomes after Selective Clamping in Robot-Assisted Partial Nephrectomy
title_full_unstemmed Functional Outcomes after Selective Clamping in Robot-Assisted Partial Nephrectomy
title_short Functional Outcomes after Selective Clamping in Robot-Assisted Partial Nephrectomy
title_sort functional outcomes after selective clamping in robot-assisted partial nephrectomy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572118/
https://www.ncbi.nlm.nih.gov/pubmed/36233518
http://dx.doi.org/10.3390/jcm11195648
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