Cargando…
Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys
Magnesium alloys are attractive candidates for use as temporary fixation devices in osteosynthesis because they have a density and Young’s modulus similar to those of cortical bone. One of the main requirements for biodegradable implants is its substitution by tissues during the healing process. In...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572374/ https://www.ncbi.nlm.nih.gov/pubmed/36234190 http://dx.doi.org/10.3390/ma15196849 |
_version_ | 1784810598034309120 |
---|---|
author | Bazhenov, Viacheslav Li, Anna Tavolzhanskii, Stanislav Bazlov, Andrey Tabachkova, Natalia Koltygin, Andrey Komissarov, Alexander Shin, Kwang Seon |
author_facet | Bazhenov, Viacheslav Li, Anna Tavolzhanskii, Stanislav Bazlov, Andrey Tabachkova, Natalia Koltygin, Andrey Komissarov, Alexander Shin, Kwang Seon |
author_sort | Bazhenov, Viacheslav |
collection | PubMed |
description | Magnesium alloys are attractive candidates for use as temporary fixation devices in osteosynthesis because they have a density and Young’s modulus similar to those of cortical bone. One of the main requirements for biodegradable implants is its substitution by tissues during the healing process. In this article, the Mg–Zn–Ga–(Y) alloys were investigated that potentially can increase the bone growth rate by release of Ga ions during the degradation process. Previously, the effectiveness of Ga ions on bone tissue regeneration has been proved by clinical tests. This work is the first systematic study on the microstructure and mechanical properties of Mg–Zn–Y alloys containing Ga as an additional major alloying element prepared by the hot-extrusion process. The microstructure and phase composition of the Mg–Zn–Ga–(Y) alloys in as-cast, heat-treated, and extruded conditions were analyzed. In addition, it was shown that the use of hot extrusion produces Mg–Zn–Ga–(Y) alloys with favorable mechanical properties. The tensile yield strength, ultimate tensile strength, and elongation at fracture of the MgZn4Ga4 alloy extruded at 150 °C were 256 MPa, 343 MPa, and 14.2%, respectively. Overall, MgZn4Ga4 alloy is a perspective for applications in implants for osteosynthesis with improved bone regeneration ability. |
format | Online Article Text |
id | pubmed-9572374 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95723742022-10-17 Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys Bazhenov, Viacheslav Li, Anna Tavolzhanskii, Stanislav Bazlov, Andrey Tabachkova, Natalia Koltygin, Andrey Komissarov, Alexander Shin, Kwang Seon Materials (Basel) Article Magnesium alloys are attractive candidates for use as temporary fixation devices in osteosynthesis because they have a density and Young’s modulus similar to those of cortical bone. One of the main requirements for biodegradable implants is its substitution by tissues during the healing process. In this article, the Mg–Zn–Ga–(Y) alloys were investigated that potentially can increase the bone growth rate by release of Ga ions during the degradation process. Previously, the effectiveness of Ga ions on bone tissue regeneration has been proved by clinical tests. This work is the first systematic study on the microstructure and mechanical properties of Mg–Zn–Y alloys containing Ga as an additional major alloying element prepared by the hot-extrusion process. The microstructure and phase composition of the Mg–Zn–Ga–(Y) alloys in as-cast, heat-treated, and extruded conditions were analyzed. In addition, it was shown that the use of hot extrusion produces Mg–Zn–Ga–(Y) alloys with favorable mechanical properties. The tensile yield strength, ultimate tensile strength, and elongation at fracture of the MgZn4Ga4 alloy extruded at 150 °C were 256 MPa, 343 MPa, and 14.2%, respectively. Overall, MgZn4Ga4 alloy is a perspective for applications in implants for osteosynthesis with improved bone regeneration ability. MDPI 2022-10-02 /pmc/articles/PMC9572374/ /pubmed/36234190 http://dx.doi.org/10.3390/ma15196849 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bazhenov, Viacheslav Li, Anna Tavolzhanskii, Stanislav Bazlov, Andrey Tabachkova, Natalia Koltygin, Andrey Komissarov, Alexander Shin, Kwang Seon Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys |
title | Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys |
title_full | Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys |
title_fullStr | Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys |
title_full_unstemmed | Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys |
title_short | Microstructure and Mechanical Properties of Hot-Extruded Mg–Zn–Ga–(Y) Biodegradable Alloys |
title_sort | microstructure and mechanical properties of hot-extruded mg–zn–ga–(y) biodegradable alloys |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572374/ https://www.ncbi.nlm.nih.gov/pubmed/36234190 http://dx.doi.org/10.3390/ma15196849 |
work_keys_str_mv | AT bazhenovviacheslav microstructureandmechanicalpropertiesofhotextrudedmgzngaybiodegradablealloys AT lianna microstructureandmechanicalpropertiesofhotextrudedmgzngaybiodegradablealloys AT tavolzhanskiistanislav microstructureandmechanicalpropertiesofhotextrudedmgzngaybiodegradablealloys AT bazlovandrey microstructureandmechanicalpropertiesofhotextrudedmgzngaybiodegradablealloys AT tabachkovanatalia microstructureandmechanicalpropertiesofhotextrudedmgzngaybiodegradablealloys AT koltyginandrey microstructureandmechanicalpropertiesofhotextrudedmgzngaybiodegradablealloys AT komissarovalexander microstructureandmechanicalpropertiesofhotextrudedmgzngaybiodegradablealloys AT shinkwangseon microstructureandmechanicalpropertiesofhotextrudedmgzngaybiodegradablealloys |