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Do Men and Women Have a Different Association between Fear-Avoidance and Pain Intensity in Chronic Pain? An Experience Sampling Method Cohort-Study

Background: Fear-avoidance is one of the factors associated with chronic pain. However, it remains unclear whether the association between fear-avoidance and pain depends on sex. The present study aimed to investigate whether the association between fear-avoidance and pain intensity differed between...

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Autores principales: Waardenburg, Sophie, Visseren, Lars, van Daal, Elke, Brouwer, Brigitte, van Zundert, Jan, van Kuijk, Sander M. J., Lousberg, Richel, Jongen, Ellen M. M., Leue, Carsten, de Meij, Nelleke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572454/
https://www.ncbi.nlm.nih.gov/pubmed/36233383
http://dx.doi.org/10.3390/jcm11195515
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author Waardenburg, Sophie
Visseren, Lars
van Daal, Elke
Brouwer, Brigitte
van Zundert, Jan
van Kuijk, Sander M. J.
Lousberg, Richel
Jongen, Ellen M. M.
Leue, Carsten
de Meij, Nelleke
author_facet Waardenburg, Sophie
Visseren, Lars
van Daal, Elke
Brouwer, Brigitte
van Zundert, Jan
van Kuijk, Sander M. J.
Lousberg, Richel
Jongen, Ellen M. M.
Leue, Carsten
de Meij, Nelleke
author_sort Waardenburg, Sophie
collection PubMed
description Background: Fear-avoidance is one of the factors associated with chronic pain. However, it remains unclear whether the association between fear-avoidance and pain depends on sex. The present study aimed to investigate whether the association between fear-avoidance and pain intensity differed between men and women in chronic pain patients. Additionally, the potential confounding effect of affective experiences on the association between fear-avoidance and pain intensity was analyzed. Method: This cohort study included hospital referred chronic pain patients (n = 45). Short momentary assessment questions according to the experience sampling method (ESM) were used to repeatedly assess patients’ pain intensity, level of fear-avoidance and positive as well as negative affect during their daily life. Linear mixed-effects models were applied in the statistical analysis. Unadjusted and adjusted models were made, in which the latter corrected for statistically significant affective experiences and baseline variables, taking the Aikake Information Criterion into account to assess a better model of fit. Results: The results demonstrated an association between fear-avoidance and pain intensity that differed for men and women. In men (n = 13), no association between these variables was found (−0.04 (95% CI: −0.14, 0.06) with a p-value of 0.48), whereas in women (n = 32), an increase in fear-avoidance was associated with a (slight) increase in pain intensity (0.18 (95% CI 0.06, 0.30) with a p-value of 0.003). Affect did not confound the above-mentioned findings. Conclusion: Our data supports previous research highlighting the importance of sex differences in pain experience. These findings may be relevant for clinicians to consider more personalized (i.e., gender specific) pain management in chronic pain patients.
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spelling pubmed-95724542022-10-17 Do Men and Women Have a Different Association between Fear-Avoidance and Pain Intensity in Chronic Pain? An Experience Sampling Method Cohort-Study Waardenburg, Sophie Visseren, Lars van Daal, Elke Brouwer, Brigitte van Zundert, Jan van Kuijk, Sander M. J. Lousberg, Richel Jongen, Ellen M. M. Leue, Carsten de Meij, Nelleke J Clin Med Article Background: Fear-avoidance is one of the factors associated with chronic pain. However, it remains unclear whether the association between fear-avoidance and pain depends on sex. The present study aimed to investigate whether the association between fear-avoidance and pain intensity differed between men and women in chronic pain patients. Additionally, the potential confounding effect of affective experiences on the association between fear-avoidance and pain intensity was analyzed. Method: This cohort study included hospital referred chronic pain patients (n = 45). Short momentary assessment questions according to the experience sampling method (ESM) were used to repeatedly assess patients’ pain intensity, level of fear-avoidance and positive as well as negative affect during their daily life. Linear mixed-effects models were applied in the statistical analysis. Unadjusted and adjusted models were made, in which the latter corrected for statistically significant affective experiences and baseline variables, taking the Aikake Information Criterion into account to assess a better model of fit. Results: The results demonstrated an association between fear-avoidance and pain intensity that differed for men and women. In men (n = 13), no association between these variables was found (−0.04 (95% CI: −0.14, 0.06) with a p-value of 0.48), whereas in women (n = 32), an increase in fear-avoidance was associated with a (slight) increase in pain intensity (0.18 (95% CI 0.06, 0.30) with a p-value of 0.003). Affect did not confound the above-mentioned findings. Conclusion: Our data supports previous research highlighting the importance of sex differences in pain experience. These findings may be relevant for clinicians to consider more personalized (i.e., gender specific) pain management in chronic pain patients. MDPI 2022-09-20 /pmc/articles/PMC9572454/ /pubmed/36233383 http://dx.doi.org/10.3390/jcm11195515 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Waardenburg, Sophie
Visseren, Lars
van Daal, Elke
Brouwer, Brigitte
van Zundert, Jan
van Kuijk, Sander M. J.
Lousberg, Richel
Jongen, Ellen M. M.
Leue, Carsten
de Meij, Nelleke
Do Men and Women Have a Different Association between Fear-Avoidance and Pain Intensity in Chronic Pain? An Experience Sampling Method Cohort-Study
title Do Men and Women Have a Different Association between Fear-Avoidance and Pain Intensity in Chronic Pain? An Experience Sampling Method Cohort-Study
title_full Do Men and Women Have a Different Association between Fear-Avoidance and Pain Intensity in Chronic Pain? An Experience Sampling Method Cohort-Study
title_fullStr Do Men and Women Have a Different Association between Fear-Avoidance and Pain Intensity in Chronic Pain? An Experience Sampling Method Cohort-Study
title_full_unstemmed Do Men and Women Have a Different Association between Fear-Avoidance and Pain Intensity in Chronic Pain? An Experience Sampling Method Cohort-Study
title_short Do Men and Women Have a Different Association between Fear-Avoidance and Pain Intensity in Chronic Pain? An Experience Sampling Method Cohort-Study
title_sort do men and women have a different association between fear-avoidance and pain intensity in chronic pain? an experience sampling method cohort-study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572454/
https://www.ncbi.nlm.nih.gov/pubmed/36233383
http://dx.doi.org/10.3390/jcm11195515
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