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Brasesquilignan A–E, Five New Furofurans Lignans from Selaginella braunii Baker
Five new furofurans lignans, Brasesquilignan A–E (1–5), were isolated from the aqueous ethanol extract of Selaginella braunii Baker. Their structures were elucidated by extensive analysis of NMR and HRESIMS data. Their absolute configurations were determined by CD spectra, enzymatic hydrolysis, and...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572557/ https://www.ncbi.nlm.nih.gov/pubmed/36234885 http://dx.doi.org/10.3390/molecules27196349 |
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author | Cheng, Fei Wu, Jianping Zhang, Yan Wang, Yuyan Li, Guihua Zeng, Hongliang He, Xiaoai Deng, Guiming Tan, Jianbin Long, Hongping Zeng, Puhua Liu, Yiheng Zhu, Gangzhi Chen, Zuhui Xu, Kangping |
author_facet | Cheng, Fei Wu, Jianping Zhang, Yan Wang, Yuyan Li, Guihua Zeng, Hongliang He, Xiaoai Deng, Guiming Tan, Jianbin Long, Hongping Zeng, Puhua Liu, Yiheng Zhu, Gangzhi Chen, Zuhui Xu, Kangping |
author_sort | Cheng, Fei |
collection | PubMed |
description | Five new furofurans lignans, Brasesquilignan A–E (1–5), were isolated from the aqueous ethanol extract of Selaginella braunii Baker. Their structures were elucidated by extensive analysis of NMR and HRESIMS data. Their absolute configurations were determined by CD spectra, enzymatic hydrolysis, and GCMS analysis. Furthermore, all compounds were evaluated for anti-proliferative activities against various human cancer cellsin vitro. Compounds 2 and 3 exhibited weak inhibitorypotency against five human cancer cells. |
format | Online Article Text |
id | pubmed-9572557 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95725572022-10-17 Brasesquilignan A–E, Five New Furofurans Lignans from Selaginella braunii Baker Cheng, Fei Wu, Jianping Zhang, Yan Wang, Yuyan Li, Guihua Zeng, Hongliang He, Xiaoai Deng, Guiming Tan, Jianbin Long, Hongping Zeng, Puhua Liu, Yiheng Zhu, Gangzhi Chen, Zuhui Xu, Kangping Molecules Article Five new furofurans lignans, Brasesquilignan A–E (1–5), were isolated from the aqueous ethanol extract of Selaginella braunii Baker. Their structures were elucidated by extensive analysis of NMR and HRESIMS data. Their absolute configurations were determined by CD spectra, enzymatic hydrolysis, and GCMS analysis. Furthermore, all compounds were evaluated for anti-proliferative activities against various human cancer cellsin vitro. Compounds 2 and 3 exhibited weak inhibitorypotency against five human cancer cells. MDPI 2022-09-26 /pmc/articles/PMC9572557/ /pubmed/36234885 http://dx.doi.org/10.3390/molecules27196349 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Cheng, Fei Wu, Jianping Zhang, Yan Wang, Yuyan Li, Guihua Zeng, Hongliang He, Xiaoai Deng, Guiming Tan, Jianbin Long, Hongping Zeng, Puhua Liu, Yiheng Zhu, Gangzhi Chen, Zuhui Xu, Kangping Brasesquilignan A–E, Five New Furofurans Lignans from Selaginella braunii Baker |
title | Brasesquilignan A–E, Five New Furofurans Lignans from Selaginella braunii Baker |
title_full | Brasesquilignan A–E, Five New Furofurans Lignans from Selaginella braunii Baker |
title_fullStr | Brasesquilignan A–E, Five New Furofurans Lignans from Selaginella braunii Baker |
title_full_unstemmed | Brasesquilignan A–E, Five New Furofurans Lignans from Selaginella braunii Baker |
title_short | Brasesquilignan A–E, Five New Furofurans Lignans from Selaginella braunii Baker |
title_sort | brasesquilignan a–e, five new furofurans lignans from selaginella braunii baker |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572557/ https://www.ncbi.nlm.nih.gov/pubmed/36234885 http://dx.doi.org/10.3390/molecules27196349 |
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