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Energy Drinks Decrease Left Ventricular Efficiency in Healthy Children and Teenagers: A Randomized Trial

Background: Minors are considered the main consumer group of energy drinks (EDs). The aim of this study was to investigate the acute effects of ED consumption on left ventricular (LV) hemodynamics and efficiency in healthy children and teenagers. Methods: This study was a randomized, single-blind, p...

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Autores principales: Oberhoffer, Felix Sebastian, Li, Pengzhu, Jakob, André, Dalla-Pozza, Robert, Haas, Nikolaus Alexander, Mandilaras, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572576/
https://www.ncbi.nlm.nih.gov/pubmed/36236307
http://dx.doi.org/10.3390/s22197209
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author Oberhoffer, Felix Sebastian
Li, Pengzhu
Jakob, André
Dalla-Pozza, Robert
Haas, Nikolaus Alexander
Mandilaras, Guido
author_facet Oberhoffer, Felix Sebastian
Li, Pengzhu
Jakob, André
Dalla-Pozza, Robert
Haas, Nikolaus Alexander
Mandilaras, Guido
author_sort Oberhoffer, Felix Sebastian
collection PubMed
description Background: Minors are considered the main consumer group of energy drinks (EDs). The aim of this study was to investigate the acute effects of ED consumption on left ventricular (LV) hemodynamics and efficiency in healthy children and teenagers. Methods: This study was a randomized, single-blind, placebo-controlled, crossover clinical trial. Study participants consumed a weight-adjusted amount of an ED or a placebo on two consecutive days. LV hemodynamics and efficiency parameters were evaluated non-invasively by generating LV pressure–volume loops (PVLs) through simultaneous echocardiography and blood pressure measurement. Results: A total of 24 children and teenagers (14.90 ± 2.27 years, 13 male) were included in the present study. Conventional echocardiographic parameters of LV function did not show significant differences between both beverage groups. The non-invasive generation of LV PVLs revealed a significantly lower cardiac efficiency 240 min after the ED consumption compared to the placebo intake (140.72 (133.21–149.73) mmHg vs. 135.60 (124.78–140.33) mmHg, p < 0.01). Conclusions: Acute ED consumption is associated with a significantly lower cardiac efficiency in healthy minors. The generation of non-invasive LV PVLs might be beneficial in the assessment of subtle changes in LV efficiency. Further studies need to investigate the influence of chronic ED consumption on LV function and morphology.
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spelling pubmed-95725762022-10-17 Energy Drinks Decrease Left Ventricular Efficiency in Healthy Children and Teenagers: A Randomized Trial Oberhoffer, Felix Sebastian Li, Pengzhu Jakob, André Dalla-Pozza, Robert Haas, Nikolaus Alexander Mandilaras, Guido Sensors (Basel) Article Background: Minors are considered the main consumer group of energy drinks (EDs). The aim of this study was to investigate the acute effects of ED consumption on left ventricular (LV) hemodynamics and efficiency in healthy children and teenagers. Methods: This study was a randomized, single-blind, placebo-controlled, crossover clinical trial. Study participants consumed a weight-adjusted amount of an ED or a placebo on two consecutive days. LV hemodynamics and efficiency parameters were evaluated non-invasively by generating LV pressure–volume loops (PVLs) through simultaneous echocardiography and blood pressure measurement. Results: A total of 24 children and teenagers (14.90 ± 2.27 years, 13 male) were included in the present study. Conventional echocardiographic parameters of LV function did not show significant differences between both beverage groups. The non-invasive generation of LV PVLs revealed a significantly lower cardiac efficiency 240 min after the ED consumption compared to the placebo intake (140.72 (133.21–149.73) mmHg vs. 135.60 (124.78–140.33) mmHg, p < 0.01). Conclusions: Acute ED consumption is associated with a significantly lower cardiac efficiency in healthy minors. The generation of non-invasive LV PVLs might be beneficial in the assessment of subtle changes in LV efficiency. Further studies need to investigate the influence of chronic ED consumption on LV function and morphology. MDPI 2022-09-23 /pmc/articles/PMC9572576/ /pubmed/36236307 http://dx.doi.org/10.3390/s22197209 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Oberhoffer, Felix Sebastian
Li, Pengzhu
Jakob, André
Dalla-Pozza, Robert
Haas, Nikolaus Alexander
Mandilaras, Guido
Energy Drinks Decrease Left Ventricular Efficiency in Healthy Children and Teenagers: A Randomized Trial
title Energy Drinks Decrease Left Ventricular Efficiency in Healthy Children and Teenagers: A Randomized Trial
title_full Energy Drinks Decrease Left Ventricular Efficiency in Healthy Children and Teenagers: A Randomized Trial
title_fullStr Energy Drinks Decrease Left Ventricular Efficiency in Healthy Children and Teenagers: A Randomized Trial
title_full_unstemmed Energy Drinks Decrease Left Ventricular Efficiency in Healthy Children and Teenagers: A Randomized Trial
title_short Energy Drinks Decrease Left Ventricular Efficiency in Healthy Children and Teenagers: A Randomized Trial
title_sort energy drinks decrease left ventricular efficiency in healthy children and teenagers: a randomized trial
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572576/
https://www.ncbi.nlm.nih.gov/pubmed/36236307
http://dx.doi.org/10.3390/s22197209
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