Cargando…

6,6′-((Methylazanedyl)bis(methylene))bis(2,4-dimethylphenol) Induces Autophagic Associated Cell Death through mTOR-Mediated Autophagy in Lung Cancer

Autophagy is the multistep mechanism for the elimination of damaged organelles and misfolded proteins. This mechanism is preceded and may induce other program cell deaths such as apoptosis. This study unraveled the potential pharmacological effect of 24MD in inducing the autophagy of lung cancer cel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sriratanasak, Nicharat, Wattanathana, Worawat, Chanvorachote, Pithi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572635/ https://www.ncbi.nlm.nih.gov/pubmed/36234769 http://dx.doi.org/10.3390/molecules27196230

Ejemplares similares

Crystal structure and Hirshfeld surface analysis of the product of the ring-opening reaction of a dihydrobenzoxazine: 6,6′-[(cyclohexylazanediyl)bis(methylene)]bis(2,4-dimethylphenol)
por: Wannapaiboon, Suttipong, et al.
Publicado: (2020)

Artonin F Induces the Ubiquitin-Proteasomal Degradation of c-Met and Decreases Akt-mTOR Signaling
por: Soonnarong, Rapeepun, et al.
Publicado: (2022)

Cisplatin Induces Senescent Lung Cancer Cell-Mediated Stemness Induction via GRP78/Akt-Dependent Mechanism
por: Sriratanasak, Nicharat, et al.
Publicado: (2022)

2-{[(2-Hydroxy-3,5-dimethylbenzyl)(methyl)amino]methyl}-4,6-dimethylphenol
por: Veranitisagul, Chatchai, et al.
Publicado: (2012)

4,4′-Diethyl-2,2′-[(N-cyclohexylimino)bis(methylene)]diphenol
por: Wattanathana, Worawat, et al.
Publicado: (2012)

Hydroquinone 5-O-Cinnamoyl Ester of Renieramycin M Suppresses Lung Cancer Stem Cells by Targeting Akt and Destabilizes c-Myc
por: Hongwiangchan, Nattamon, et al.
Publicado: (2021)

Artocarpin Targets Focal Adhesion Kinase-Dependent Epithelial to Mesenchymal Transition and Suppresses Migratory-Associated Integrins in Lung Cancer Cells
por: Nonpanya, Nongyao, et al.
Publicado: (2021)

6,6′-Dimethyl-2,2′-[imidazolidine-1,3-diylbis(methylene)]diphenol
por: Rivera, Augusto, et al.
Publicado: (2014)

Targeting AKT/mTOR and Bcl-2 for Autophagic and Apoptosis Cell Death in Lung Cancer: Novel Activity of a Polyphenol Compound
por: Tungsukruthai, Sucharat, et al.
Publicado: (2021)

6,6′-Dimethyl-2,2′-[1,3-diazinane-1,3-diylbis(methylene)]diphenol
por: Rivera, Augusto, et al.
Publicado: (2012)

4,6-Dibromo-2,3-dimethylphenol
por: Liu, Qiaoru, et al.
Publicado: (2011)

4,4′-({[(Pyridine-2,6-diyl)bis(methylene)]bis(oxy)}bis(methylene))dibenzonitrile
por: Yamin, Bohari M., et al.
Publicado: (2014)

5-O-(N-Boc-l-Alanine)-Renieramycin T Induces Cancer Stem Cell Apoptosis via Targeting Akt Signaling
por: Suksamai, Darinthip, et al.
Publicado: (2022)

Crystal structure and Hirshfeld surface analysis of 6,6′-((1E,1′E)-{[1,4-phenylenebis(methylene)]bis(azanylylidene)}bis(methaneylylidene))bis(2-methoxyphenol)
por: Kansiz, Sevgi, et al.
Publicado: (2022)

Ovalitenone Inhibits the Migration of Lung Cancer Cells via the Suppression of AKT/mTOR and Epithelial-to-Mesenchymal Transition
por: Sanookpan, Kittipong, et al.
Publicado: (2021)

4-tert-Butylpyridinium chloride–4,4′-(propane-2,2-diyl)bis(2,6-dimethylphenol)–toluene (2/2/1)
por: Nielson, Alastair J., et al.
Publicado: (2014)

Redetermination of 3,5-dimethylphenol
por: Betz, Richard, et al.
Publicado: (2011)

Akt/mTOR Targeting Activity of Resveratrol Derivatives in Non-Small Lung Cancer
por: Innets, Bhurichaya, et al.
Publicado: (2022)

N,N′-Bis[(E)-(6-methyl-2-pyridyl)methylene]hexane-1,6-diamine
por: Ramos Silva, Manuela, et al.
Publicado: (2009)

Methylene bis(dithiobenzoate)
por: Liang, Yao-Ren, et al.
Publicado: (2008)

Crystal structures of bis- and hexakis[(6,6′-dihydroxybipyridine)copper(II)] nitrate coordination complexes
por: Gerlach, Deidra L., et al.
Publicado: (2015)

6,6′-(Pyridine-2,6-diyl)bis(pyrrolo[3,4-b]pyridine-5,7-dione)
por: Van der Berg, P. C. W., et al.
Publicado: (2011)

6,6′-Dimethoxy-2,2′-[(hexane-1,6-diyldioxy)bis(nitrilomethylidyne)]diphenol
por: Dong, Wen-Kui, et al.
Publicado: (2008)

(4,4′,6,6′-Tetra-tert-butyl-2,2′-{[2-(dimethylamino)ethyl]nitrilobis(methylene)}diphenolato)dioxidomolybdenum(VI) chloroform monosolvate
por: Lei, Xiangyang, et al.
Publicado: (2011)

1,2-Bis[bis(methylsulfanyl)methylene]hydrazine
por: Driss, Mohamed, et al.
Publicado: (2008)

6,6′-Diethoxy-2,2′-[propane-1,2-diylbis(nitrilomethylidyne)]diphenol
por: Jia, Zhen
Publicado: (2009)

Huaier Extract Induces Autophagic Cell Death by Inhibiting the mTOR/S6K Pathway in Breast Cancer Cells
por: Wang, Xiaolong, et al.
Publicado: (2015)

Bis{μ-4,4′,6,6′-tetrabromo-2,2′-[o-phenylenebis(nitrilomethylidyne)]diphenolato}bis[(dimethylformamide)cadmium(II)]
por: Shi, Shaomin, et al.
Publicado: (2007)

2,2′-{[(2,2′-Diethoxy-1,1′-binaphthalene-6,6′-diyl)bis(4,1-phenylene)]bis(methanylylidene)}dimalononitrile
por: Chen, Shikun
Publicado: (2012)

6,6′-Dihydroxy-2,2′-[(butane-1,4-diyldioxy)bis(nitrilomethylidyne)]diphenol
por: Dong, Wen-Kui, et al.
Publicado: (2008)

(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis(diphenylphosphane) P,P′-dioxide dihydrate
por: Dai, Dongmei, et al.
Publicado: (2012)

6,6′-Diethoxy-2,2′-[propane-1,3-diyldioxybis(nitrilomethylidyne)]diphenol
por: Wang, Li, et al.
Publicado: (2010)

6,6′-Dihydroxy-2,2′-[(propane-1,3-diyldioxy)bis(nitrilomethylidyne)]diphenol
por: Dong, Wen-Kui, et al.
Publicado: (2008)

6,6′-Di-tert-butyl-2,2′-[1,2-phenylenebis(nitrilomethylidyne)]diphenol
por: Eltayeb, Naser Eltaher, et al.
Publicado: (2009)

6,6′-Dihydroxy-2,2′-[(pentane-1,5-diyldioxy)bis(nitrilomethylidyne)]diphenol
por: Dong, Wen-Kui, et al.
Publicado: (2008)

(E,E)-6,6′-Dimethoxy-2,2′-[o-phenylenebis(nitrilomethylidyne)]diphenol
por: Wang, Yong, et al.
Publicado: (2009)

Synthesis and Reactivity of a Bis-Strained Alkyne Derived from 1,1′-Biphenyl-2,2′,6,6′-tetrol
por: Knighton, Richard C., et al.
Publicado: (2019)

6,6′-Dimethoxy-2,2′-[p-phenylenebis(nitrilomethylidyne)]diphenol chloroform disolvate
por: Al-Douh, Mohammed H., et al.
Publicado: (2009)

6,6′-Dimethoxy-2,2′-[(cyclohexane-1,2-diyl)bis(nitrilomethylidyne)]diphenol
por: Zhang, Qian, et al.
Publicado: (2010)

Conversion of Methane into Methanol Using the [6,6′-(2,2′-Bipyridine-6,6′-Diyl)bis(1,3,5-Triazine-2,4-Diamine)](Nitrato-O)Copper(II) Complex in a Solid Electrolyte Reactor Fuel Cell Type
por: Garcia, Luis M. S., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_n8h9upq13i65udhqm0mn7piv77