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First Discovery of Cholesterol-Lowering Activity of Parthenolide as NPC1L1 Inhibitor

Elevated cholesterol significantly increases the risk of developing atherosclerosis and coronary heart disease. The key to treating hypercholesterolemia is lowering plasma cholesterol levels. There have been no studies on the cholesterol-lowering potential of parthenolide (PTL), a naturally occurrin...

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Detalles Bibliográficos
Autores principales: Liu, Wenjing, Liang, Bing, Zeng, Jun, Meng, Jingsen, Shi, Lingyu, Yang, Shanbo, Chang, Jing, Wang, Chao, Hu, Xiaokun, Wang, Xufu, Han, Na, Lu, Chenghui, Li, Jiao, Wang, Congcong, Li, Huanting, Zhang, Renshuai, Xing, Dongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572688/
https://www.ncbi.nlm.nih.gov/pubmed/36234807
http://dx.doi.org/10.3390/molecules27196270