Synthesis of Novel Benzimidazole-Based Thiazole Derivatives as Multipotent Inhibitors of α-Amylase and α-Glucosidase: In Vitro Evaluation along with Molecular Docking Study

In this study, hybrid analogs of benzimidazole containing a thiazole moiety (1–17) were afforded and then tested for their ability to inhibit α-amylase and α-glucosidase when compared to acarbose as a standard drug. The recently available analogs showed a wide variety of inhibitory potentials that r...

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Detalles Bibliográficos
Autores principales: Hussain, Rafaqat, Iqbal, Shahid, Shah, Mazloom, Rehman, Wajid, Khan, Shoaib, Rasheed, Liaqat, Rahim, Fazal, Dera, Ayed A., Kehili, Sana, Elkaeed, Eslam B., Awwad, Nasser S., Bajaber, Majed A., Alahmdi, Mohammed Issa, Alrbyawi, Hamad, Alsaab, Hashem O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572811/
https://www.ncbi.nlm.nih.gov/pubmed/36234994
http://dx.doi.org/10.3390/molecules27196457

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