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Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study
Cross-sectional studies have demonstrated an association between abdominal obesity, determined by waist circumference (WC), and vitamin D (25(OH)D) deficiency in older adults. However, longitudinal evidence is based only on general obesity determined using body mass index (BMI). We investigated whet...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572900/ https://www.ncbi.nlm.nih.gov/pubmed/36235815 http://dx.doi.org/10.3390/nu14194164 |
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author | da Silva, Thaís Barros Pereira Luiz, Mariane Marques Delinocente, Maicon Luís Bicigo Steptoe, Andrew de Oliveira, Cesar Alexandre, Tiago da Silva |
author_facet | da Silva, Thaís Barros Pereira Luiz, Mariane Marques Delinocente, Maicon Luís Bicigo Steptoe, Andrew de Oliveira, Cesar Alexandre, Tiago da Silva |
author_sort | da Silva, Thaís Barros Pereira |
collection | PubMed |
description | Cross-sectional studies have demonstrated an association between abdominal obesity, determined by waist circumference (WC), and vitamin D (25(OH)D) deficiency in older adults. However, longitudinal evidence is based only on general obesity determined using body mass index (BMI). We investigated whether abdominal obesity is associated with the incidence of 25(OH)D insufficiency (>30 and ≤50 nmol/L) and deficiency (≤30 nmol/L), and whether vitamin D supplementation modifies these associations. We included 2459 participants aged ≥50 years from the English Longitudinal Study of Ageing (ELSA) with 25(OH)D sufficiency (>50 nmol/L) at baseline. Abdominal obesity was defined as >88 cm for women and >102 cm for men. After 4 years, 25(OH)D concentrations were reassessed. Multinomial logistic regression models controlled by covariates were performed. Abdominal obesity increased the risk of the incidence of 25(OH)D insufficiency (RRR = 1.36; 95% CI: 1.01–1.83) and deficiency (RRR = 1.64; 95% CI: 1.05–2.58). These risks were maintained when excluding individuals who took vitamin D supplementation (RRR = 1.38; 95% CI: 1.02–1.88) and (RRR = 1.62; 95% CI: 1.02–2.56). Abdominal obesity is associated with the risk of incidence of low 25(OH)D concentrations. WC seems to be an adequate tool for screening individuals with obesity and at potential risk of developing these conditions. |
format | Online Article Text |
id | pubmed-9572900 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95729002022-10-17 Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study da Silva, Thaís Barros Pereira Luiz, Mariane Marques Delinocente, Maicon Luís Bicigo Steptoe, Andrew de Oliveira, Cesar Alexandre, Tiago da Silva Nutrients Article Cross-sectional studies have demonstrated an association between abdominal obesity, determined by waist circumference (WC), and vitamin D (25(OH)D) deficiency in older adults. However, longitudinal evidence is based only on general obesity determined using body mass index (BMI). We investigated whether abdominal obesity is associated with the incidence of 25(OH)D insufficiency (>30 and ≤50 nmol/L) and deficiency (≤30 nmol/L), and whether vitamin D supplementation modifies these associations. We included 2459 participants aged ≥50 years from the English Longitudinal Study of Ageing (ELSA) with 25(OH)D sufficiency (>50 nmol/L) at baseline. Abdominal obesity was defined as >88 cm for women and >102 cm for men. After 4 years, 25(OH)D concentrations were reassessed. Multinomial logistic regression models controlled by covariates were performed. Abdominal obesity increased the risk of the incidence of 25(OH)D insufficiency (RRR = 1.36; 95% CI: 1.01–1.83) and deficiency (RRR = 1.64; 95% CI: 1.05–2.58). These risks were maintained when excluding individuals who took vitamin D supplementation (RRR = 1.38; 95% CI: 1.02–1.88) and (RRR = 1.62; 95% CI: 1.02–2.56). Abdominal obesity is associated with the risk of incidence of low 25(OH)D concentrations. WC seems to be an adequate tool for screening individuals with obesity and at potential risk of developing these conditions. MDPI 2022-10-07 /pmc/articles/PMC9572900/ /pubmed/36235815 http://dx.doi.org/10.3390/nu14194164 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article da Silva, Thaís Barros Pereira Luiz, Mariane Marques Delinocente, Maicon Luís Bicigo Steptoe, Andrew de Oliveira, Cesar Alexandre, Tiago da Silva Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study |
title | Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study |
title_full | Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study |
title_fullStr | Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study |
title_full_unstemmed | Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study |
title_short | Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study |
title_sort | is abdominal obesity a risk factor for the incidence of vitamin d insufficiency and deficiency in older adults? evidence from the elsa study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572900/ https://www.ncbi.nlm.nih.gov/pubmed/36235815 http://dx.doi.org/10.3390/nu14194164 |
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