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Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study

Cross-sectional studies have demonstrated an association between abdominal obesity, determined by waist circumference (WC), and vitamin D (25(OH)D) deficiency in older adults. However, longitudinal evidence is based only on general obesity determined using body mass index (BMI). We investigated whet...

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Autores principales: da Silva, Thaís Barros Pereira, Luiz, Mariane Marques, Delinocente, Maicon Luís Bicigo, Steptoe, Andrew, de Oliveira, Cesar, Alexandre, Tiago da Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572900/
https://www.ncbi.nlm.nih.gov/pubmed/36235815
http://dx.doi.org/10.3390/nu14194164
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author da Silva, Thaís Barros Pereira
Luiz, Mariane Marques
Delinocente, Maicon Luís Bicigo
Steptoe, Andrew
de Oliveira, Cesar
Alexandre, Tiago da Silva
author_facet da Silva, Thaís Barros Pereira
Luiz, Mariane Marques
Delinocente, Maicon Luís Bicigo
Steptoe, Andrew
de Oliveira, Cesar
Alexandre, Tiago da Silva
author_sort da Silva, Thaís Barros Pereira
collection PubMed
description Cross-sectional studies have demonstrated an association between abdominal obesity, determined by waist circumference (WC), and vitamin D (25(OH)D) deficiency in older adults. However, longitudinal evidence is based only on general obesity determined using body mass index (BMI). We investigated whether abdominal obesity is associated with the incidence of 25(OH)D insufficiency (>30 and ≤50 nmol/L) and deficiency (≤30 nmol/L), and whether vitamin D supplementation modifies these associations. We included 2459 participants aged ≥50 years from the English Longitudinal Study of Ageing (ELSA) with 25(OH)D sufficiency (>50 nmol/L) at baseline. Abdominal obesity was defined as >88 cm for women and >102 cm for men. After 4 years, 25(OH)D concentrations were reassessed. Multinomial logistic regression models controlled by covariates were performed. Abdominal obesity increased the risk of the incidence of 25(OH)D insufficiency (RRR = 1.36; 95% CI: 1.01–1.83) and deficiency (RRR = 1.64; 95% CI: 1.05–2.58). These risks were maintained when excluding individuals who took vitamin D supplementation (RRR = 1.38; 95% CI: 1.02–1.88) and (RRR = 1.62; 95% CI: 1.02–2.56). Abdominal obesity is associated with the risk of incidence of low 25(OH)D concentrations. WC seems to be an adequate tool for screening individuals with obesity and at potential risk of developing these conditions.
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spelling pubmed-95729002022-10-17 Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study da Silva, Thaís Barros Pereira Luiz, Mariane Marques Delinocente, Maicon Luís Bicigo Steptoe, Andrew de Oliveira, Cesar Alexandre, Tiago da Silva Nutrients Article Cross-sectional studies have demonstrated an association between abdominal obesity, determined by waist circumference (WC), and vitamin D (25(OH)D) deficiency in older adults. However, longitudinal evidence is based only on general obesity determined using body mass index (BMI). We investigated whether abdominal obesity is associated with the incidence of 25(OH)D insufficiency (>30 and ≤50 nmol/L) and deficiency (≤30 nmol/L), and whether vitamin D supplementation modifies these associations. We included 2459 participants aged ≥50 years from the English Longitudinal Study of Ageing (ELSA) with 25(OH)D sufficiency (>50 nmol/L) at baseline. Abdominal obesity was defined as >88 cm for women and >102 cm for men. After 4 years, 25(OH)D concentrations were reassessed. Multinomial logistic regression models controlled by covariates were performed. Abdominal obesity increased the risk of the incidence of 25(OH)D insufficiency (RRR = 1.36; 95% CI: 1.01–1.83) and deficiency (RRR = 1.64; 95% CI: 1.05–2.58). These risks were maintained when excluding individuals who took vitamin D supplementation (RRR = 1.38; 95% CI: 1.02–1.88) and (RRR = 1.62; 95% CI: 1.02–2.56). Abdominal obesity is associated with the risk of incidence of low 25(OH)D concentrations. WC seems to be an adequate tool for screening individuals with obesity and at potential risk of developing these conditions. MDPI 2022-10-07 /pmc/articles/PMC9572900/ /pubmed/36235815 http://dx.doi.org/10.3390/nu14194164 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
da Silva, Thaís Barros Pereira
Luiz, Mariane Marques
Delinocente, Maicon Luís Bicigo
Steptoe, Andrew
de Oliveira, Cesar
Alexandre, Tiago da Silva
Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study
title Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study
title_full Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study
title_fullStr Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study
title_full_unstemmed Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study
title_short Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study
title_sort is abdominal obesity a risk factor for the incidence of vitamin d insufficiency and deficiency in older adults? evidence from the elsa study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572900/
https://www.ncbi.nlm.nih.gov/pubmed/36235815
http://dx.doi.org/10.3390/nu14194164
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