Cargando…
Exploring 2-Tetradecanoylimino-3-aryl-4-methyl-1,3-thiazolines Derivatives as Alkaline Phosphatase Inhibitors: Biochemical Evaluation and Computational Analysis
The current study focused on the laboratory approach in conjunction with computational methods for the synthesis and bioactivity assessment of unique 2-tetradecanoylimino-3-aryl-4-methyl-1,3-thiazolines (2a–2k). Processes included cyclizing 1-aroyl-3-arylthioureas with propan-2-one in the presence o...
Autores principales: | Ahmed, Aftab, Rehman, Sajid-ur, Ejaz, Syeda Abida, Saeed, Aamer, Ujan, Rabail, Channar, Pervaiz Ali, Mahar, Khalida, Sahito, Reshma, Albogami, Sarah M., Abbas, Qamar, Alorabi, Mohammed, Waard, Michel De, Batiha, Gaber El-Saber |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572939/ https://www.ncbi.nlm.nih.gov/pubmed/36235300 http://dx.doi.org/10.3390/molecules27196766 |
Ejemplares similares
-
Synthesis, DFT and molecular docking of novel (Z)-4-bromo-N-(4-butyl-3 (quinolin-3-yl)thiazol-2(3H)-ylidene)benzamide as elastase inhibitor
por: Mustafa, Muhammad Naeem, et al.
Publicado: (2023) -
Synthesis, Biological Evaluation, and Molecular Dynamics of Carbothioamides Derivatives as Carbonic Anhydrase II and 15-Lipoxygenase Inhibitors
por: Channar, Pervaiz Ali, et al.
Publicado: (2022) -
Synthesis, biological evaluation and in silico investigations of benzotriazole derivatives as potential inhibitors of NIMA related kinase
por: Qadri, Tahir, et al.
Publicado: (2023) -
Computational and theoretical chemistry of newly synthesized and characterized 2,2(’)-(5,5(’)-(1,4-phenylene)bis(1H-tetrazole-5,1-diyl))bis-N-acetamides
por: Ejaz, Syeda Abida, et al.
Publicado: (2023) -
Structure and surface analyses of a newly synthesized acyl thiourea derivative along with its in silico and in vitro investigations for RNR, DNA binding, urease inhibition and radical scavenging activities
por: Khalid, Aqsa, et al.
Publicado: (2022)