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Association of Coffee and Tea Consumption with the Risk of Asthma: A Prospective Cohort Study from the UK Biobank

Background: Previous observational studies investigated the relationship between coffee and tea intake and the risk of asthma, however, the conclusions were inconsistent. Further, the combined effect of coffee and tea consumption on asthma has rarely been studied. Methods: We examined associations b...

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Autores principales: Lin, Fengyu, Zhu, Yiqun, Liang, Huaying, Li, Dianwu, Jing, Danrong, Liu, Hong, Pan, Pinhua, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572944/
https://www.ncbi.nlm.nih.gov/pubmed/36235690
http://dx.doi.org/10.3390/nu14194039
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author Lin, Fengyu
Zhu, Yiqun
Liang, Huaying
Li, Dianwu
Jing, Danrong
Liu, Hong
Pan, Pinhua
Zhang, Yan
author_facet Lin, Fengyu
Zhu, Yiqun
Liang, Huaying
Li, Dianwu
Jing, Danrong
Liu, Hong
Pan, Pinhua
Zhang, Yan
author_sort Lin, Fengyu
collection PubMed
description Background: Previous observational studies investigated the relationship between coffee and tea intake and the risk of asthma, however, the conclusions were inconsistent. Further, the combined effect of coffee and tea consumption on asthma has rarely been studied. Methods: We examined associations between the self-reported intake of tea and coffee and the risk of incident asthma in a total of 424,725 participants aged from 39 to 73 years old from the UK Biobank. Cox proportional hazards models were used to estimate the associations between coffee/tea consumption and incident adult-onset asthma, adjusting for age, sex, race, smoking status, body mass index (BMI), education, and Townsend deprivation index. Results: Cox models with penalized splines showed J-shaped associations of coffee, tea, caffeinated coffee, and caffeine intake from coffee and tea with the risk of adult-onset asthma (p for nonlinear <0.01). Coffee intake of 2 to 3 cups/d (hazard ratio [HR] 0.877, 95% confidence interval [CI] 0.826–0.931) or tea intake of 0.5 to 1 cups/d (HR 0.889, 95% CI 0.816–0.968) or caffeinated coffee intake of 2 to 3 cups/d (HR 0.858, 95% CI 0.806–0.915) or combination caffeine intake from tea and coffee of 160.0 to 235.0 mg per day (HR 0.899, 95% CI 0.842–0.961) were linked with the lowest hazard ratio of incident asthma after adjustment for age, sex, race, smoking status, BMI, qualification, and Townsend deprivation index. Conclusions: Collectively, the study showed light-to-moderate coffee and tea consumption was associated with a reduced risk of adult-onset asthma and controlling total caffeine intake from coffee and tea for a moderate caffeine dose of 160.0 to 305.0 mg/day may be protective against adult-onset asthma. Further investigation on the possible preventive role of caffeine in asthma is warranted.
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spelling pubmed-95729442022-10-17 Association of Coffee and Tea Consumption with the Risk of Asthma: A Prospective Cohort Study from the UK Biobank Lin, Fengyu Zhu, Yiqun Liang, Huaying Li, Dianwu Jing, Danrong Liu, Hong Pan, Pinhua Zhang, Yan Nutrients Article Background: Previous observational studies investigated the relationship between coffee and tea intake and the risk of asthma, however, the conclusions were inconsistent. Further, the combined effect of coffee and tea consumption on asthma has rarely been studied. Methods: We examined associations between the self-reported intake of tea and coffee and the risk of incident asthma in a total of 424,725 participants aged from 39 to 73 years old from the UK Biobank. Cox proportional hazards models were used to estimate the associations between coffee/tea consumption and incident adult-onset asthma, adjusting for age, sex, race, smoking status, body mass index (BMI), education, and Townsend deprivation index. Results: Cox models with penalized splines showed J-shaped associations of coffee, tea, caffeinated coffee, and caffeine intake from coffee and tea with the risk of adult-onset asthma (p for nonlinear <0.01). Coffee intake of 2 to 3 cups/d (hazard ratio [HR] 0.877, 95% confidence interval [CI] 0.826–0.931) or tea intake of 0.5 to 1 cups/d (HR 0.889, 95% CI 0.816–0.968) or caffeinated coffee intake of 2 to 3 cups/d (HR 0.858, 95% CI 0.806–0.915) or combination caffeine intake from tea and coffee of 160.0 to 235.0 mg per day (HR 0.899, 95% CI 0.842–0.961) were linked with the lowest hazard ratio of incident asthma after adjustment for age, sex, race, smoking status, BMI, qualification, and Townsend deprivation index. Conclusions: Collectively, the study showed light-to-moderate coffee and tea consumption was associated with a reduced risk of adult-onset asthma and controlling total caffeine intake from coffee and tea for a moderate caffeine dose of 160.0 to 305.0 mg/day may be protective against adult-onset asthma. Further investigation on the possible preventive role of caffeine in asthma is warranted. MDPI 2022-09-28 /pmc/articles/PMC9572944/ /pubmed/36235690 http://dx.doi.org/10.3390/nu14194039 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lin, Fengyu
Zhu, Yiqun
Liang, Huaying
Li, Dianwu
Jing, Danrong
Liu, Hong
Pan, Pinhua
Zhang, Yan
Association of Coffee and Tea Consumption with the Risk of Asthma: A Prospective Cohort Study from the UK Biobank
title Association of Coffee and Tea Consumption with the Risk of Asthma: A Prospective Cohort Study from the UK Biobank
title_full Association of Coffee and Tea Consumption with the Risk of Asthma: A Prospective Cohort Study from the UK Biobank
title_fullStr Association of Coffee and Tea Consumption with the Risk of Asthma: A Prospective Cohort Study from the UK Biobank
title_full_unstemmed Association of Coffee and Tea Consumption with the Risk of Asthma: A Prospective Cohort Study from the UK Biobank
title_short Association of Coffee and Tea Consumption with the Risk of Asthma: A Prospective Cohort Study from the UK Biobank
title_sort association of coffee and tea consumption with the risk of asthma: a prospective cohort study from the uk biobank
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572944/
https://www.ncbi.nlm.nih.gov/pubmed/36235690
http://dx.doi.org/10.3390/nu14194039
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