A New Method for Abrin Detection Based on the Interaction between Target Molecules and Fluorescently Labeled Aptamers on Magnetic Microspheres

A quantitative structure–activity relationship (QSAR) model for the structure and affinity of abrin aptamers was established. A higher affinity abrin aptamer based on the established QSAR model was screened by site-directed mutagenesis. The fluorescence quenching effect between magnetic microspheres...

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Detalles Bibliográficos
Autores principales: Liu, Zhiwei, Tong, Zhaoyang, Wu, Yuting, Liu, Bing, Feng, Shasha, Mu, Xihui, Wang, Jiang, Du, Bin, Xu, Jianjie, Liu, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573059/
https://www.ncbi.nlm.nih.gov/pubmed/36234322
http://dx.doi.org/10.3390/ma15196977

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