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Erdafitinib Inhibits Tumorigenesis of Human Lung Adenocarcinoma A549 by Inducing S-Phase Cell-Cycle Arrest as a CDK2 Inhibitor

Lung adenocarcinoma (LADC) is the most prevalent lung cancer sub-type, and targeted therapy developed in recent years has made progress in its treatment. Erdafitinib, a potent and selective pan-FGFR tyrosine kinase inhibitor, has been confirmed to be effective for the treatment of LADC; however, the...

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Detalles Bibliográficos
Autores principales:	Meng, Xinmin, Zhu, Xue, Ji, Jiali, Zhong, Hongqin, Li, Xiyue, Zhao, Hongqing, Xie, Guijuan, Wang, Ke, Shu, Hong, Wang, Xun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573074/ https://www.ncbi.nlm.nih.gov/pubmed/36235266 http://dx.doi.org/10.3390/molecules27196733

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