Quantification of Acipimox in Plasma and Tissues by LC–MS/MS: Application to Pharmacokinetic Comparison between Normoxia and Hypoxia

This study aimed to evaluate the pharmacokinetics of acipimox in rats under simulated high altitude hypoxia conditions. A sensitive and reliable LC–MS/MS method has been established for the quantitation of acipimox in rat plasma and tissue homogenate and validated according to the guidelines of the...

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Detalles Bibliográficos
Autores principales: Shen, Xin, Li, Gaofu, Wang, Libin, Yu, Huijin, Zhou, Lei, Deng, Huifang, Wang, Ningning, Lai, Chengcai, Zhou, Wei, Gao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573116/
https://www.ncbi.nlm.nih.gov/pubmed/36234950
http://dx.doi.org/10.3390/molecules27196413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573116/
https://www.ncbi.nlm.nih.gov/pubmed/36234950
http://dx.doi.org/10.3390/molecules27196413

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