Current and Future Insights for Optimizing Antithrombotic Therapy to Reduce the Burden of Cardiovascular Ischemic Events in Patients with Acute Coronary Syndrome

The pharmacological treatment strategies for acute coronary syndrome (ACS) in recent years are constantly evolving to develop more potent antithrombotic agents, as reflected by the introduction of more novel P2Y(12) receptor inhibitors and anticoagulants to reduce the ischemic risk among ACS patient...

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Autores principales: Selvarajah, Abi, Tavenier, Anne H., Fabris, Enrico, van Leeuwen, Maarten A. H., Hermanides, Renicus S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573364/
https://www.ncbi.nlm.nih.gov/pubmed/36233469
http://dx.doi.org/10.3390/jcm11195605
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author Selvarajah, Abi
Tavenier, Anne H.
Fabris, Enrico
van Leeuwen, Maarten A. H.
Hermanides, Renicus S.
author_facet Selvarajah, Abi
Tavenier, Anne H.
Fabris, Enrico
van Leeuwen, Maarten A. H.
Hermanides, Renicus S.
author_sort Selvarajah, Abi
collection PubMed
description The pharmacological treatment strategies for acute coronary syndrome (ACS) in recent years are constantly evolving to develop more potent antithrombotic agents, as reflected by the introduction of more novel P2Y(12) receptor inhibitors and anticoagulants to reduce the ischemic risk among ACS patients. Despite the substantial improvements in the current antithrombotic regimen, a noticeable number of ACS patients continue to experience ischemic events. Providing effective ischemic risk reduction while balancing bleeding risk remains a clinical challenge. This updated review discusses the currently approved and widely used antithrombotic agents and explores newer antithrombotic treatment strategies under development for the initial phase of ACS.
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spelling pubmed-95733642022-10-17 Current and Future Insights for Optimizing Antithrombotic Therapy to Reduce the Burden of Cardiovascular Ischemic Events in Patients with Acute Coronary Syndrome Selvarajah, Abi Tavenier, Anne H. Fabris, Enrico van Leeuwen, Maarten A. H. Hermanides, Renicus S. J Clin Med Review The pharmacological treatment strategies for acute coronary syndrome (ACS) in recent years are constantly evolving to develop more potent antithrombotic agents, as reflected by the introduction of more novel P2Y(12) receptor inhibitors and anticoagulants to reduce the ischemic risk among ACS patients. Despite the substantial improvements in the current antithrombotic regimen, a noticeable number of ACS patients continue to experience ischemic events. Providing effective ischemic risk reduction while balancing bleeding risk remains a clinical challenge. This updated review discusses the currently approved and widely used antithrombotic agents and explores newer antithrombotic treatment strategies under development for the initial phase of ACS. MDPI 2022-09-23 /pmc/articles/PMC9573364/ /pubmed/36233469 http://dx.doi.org/10.3390/jcm11195605 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Selvarajah, Abi
Tavenier, Anne H.
Fabris, Enrico
van Leeuwen, Maarten A. H.
Hermanides, Renicus S.
Current and Future Insights for Optimizing Antithrombotic Therapy to Reduce the Burden of Cardiovascular Ischemic Events in Patients with Acute Coronary Syndrome
title Current and Future Insights for Optimizing Antithrombotic Therapy to Reduce the Burden of Cardiovascular Ischemic Events in Patients with Acute Coronary Syndrome
title_full Current and Future Insights for Optimizing Antithrombotic Therapy to Reduce the Burden of Cardiovascular Ischemic Events in Patients with Acute Coronary Syndrome
title_fullStr Current and Future Insights for Optimizing Antithrombotic Therapy to Reduce the Burden of Cardiovascular Ischemic Events in Patients with Acute Coronary Syndrome
title_full_unstemmed Current and Future Insights for Optimizing Antithrombotic Therapy to Reduce the Burden of Cardiovascular Ischemic Events in Patients with Acute Coronary Syndrome
title_short Current and Future Insights for Optimizing Antithrombotic Therapy to Reduce the Burden of Cardiovascular Ischemic Events in Patients with Acute Coronary Syndrome
title_sort current and future insights for optimizing antithrombotic therapy to reduce the burden of cardiovascular ischemic events in patients with acute coronary syndrome
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573364/
https://www.ncbi.nlm.nih.gov/pubmed/36233469
http://dx.doi.org/10.3390/jcm11195605
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