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The Effects of Race on Acute Kidney Injury

Racial disparities in incidence and outcomes of acute kidney injury (AKI) are pervasive and are driven in part by social inequities and other factors. It is well-documented that Black patients face higher risk of AKI and seemingly have a survival advantage compared to White counterparts. Various exp...

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Detalles Bibliográficos
Autores principales: Hassan, Muzamil Olamide, Balogun, Rasheed Abiodun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573379/
https://www.ncbi.nlm.nih.gov/pubmed/36233687
http://dx.doi.org/10.3390/jcm11195822
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author Hassan, Muzamil Olamide
Balogun, Rasheed Abiodun
author_facet Hassan, Muzamil Olamide
Balogun, Rasheed Abiodun
author_sort Hassan, Muzamil Olamide
collection PubMed
description Racial disparities in incidence and outcomes of acute kidney injury (AKI) are pervasive and are driven in part by social inequities and other factors. It is well-documented that Black patients face higher risk of AKI and seemingly have a survival advantage compared to White counterparts. Various explanations have been advanced and suggested to account for this, including differences in susceptibility to kidney injury, severity of illness, and socioeconomic factors. In this review, we try to understand and further explore the link between race and AKI using the incidence, diagnosis, and management of AKI to illustrate how race is directly related to AKI outcomes, with a focus on Black and White individuals with AKI. In particular, we explore the effect of race-adjusted estimated glomerular filtration rate (eGFR) equation on AKI prediction and discuss racial disparities in the management of AKI and how this might contribute to racial differences in AKI-related mortality among Blacks with AKI. We also identify some opportunities for future research and advocacy.
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spelling pubmed-95733792022-10-17 The Effects of Race on Acute Kidney Injury Hassan, Muzamil Olamide Balogun, Rasheed Abiodun J Clin Med Review Racial disparities in incidence and outcomes of acute kidney injury (AKI) are pervasive and are driven in part by social inequities and other factors. It is well-documented that Black patients face higher risk of AKI and seemingly have a survival advantage compared to White counterparts. Various explanations have been advanced and suggested to account for this, including differences in susceptibility to kidney injury, severity of illness, and socioeconomic factors. In this review, we try to understand and further explore the link between race and AKI using the incidence, diagnosis, and management of AKI to illustrate how race is directly related to AKI outcomes, with a focus on Black and White individuals with AKI. In particular, we explore the effect of race-adjusted estimated glomerular filtration rate (eGFR) equation on AKI prediction and discuss racial disparities in the management of AKI and how this might contribute to racial differences in AKI-related mortality among Blacks with AKI. We also identify some opportunities for future research and advocacy. MDPI 2022-09-30 /pmc/articles/PMC9573379/ /pubmed/36233687 http://dx.doi.org/10.3390/jcm11195822 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hassan, Muzamil Olamide
Balogun, Rasheed Abiodun
The Effects of Race on Acute Kidney Injury
title The Effects of Race on Acute Kidney Injury
title_full The Effects of Race on Acute Kidney Injury
title_fullStr The Effects of Race on Acute Kidney Injury
title_full_unstemmed The Effects of Race on Acute Kidney Injury
title_short The Effects of Race on Acute Kidney Injury
title_sort effects of race on acute kidney injury
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573379/
https://www.ncbi.nlm.nih.gov/pubmed/36233687
http://dx.doi.org/10.3390/jcm11195822
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