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The Effects of Race on Acute Kidney Injury
Racial disparities in incidence and outcomes of acute kidney injury (AKI) are pervasive and are driven in part by social inequities and other factors. It is well-documented that Black patients face higher risk of AKI and seemingly have a survival advantage compared to White counterparts. Various exp...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573379/ https://www.ncbi.nlm.nih.gov/pubmed/36233687 http://dx.doi.org/10.3390/jcm11195822 |
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author | Hassan, Muzamil Olamide Balogun, Rasheed Abiodun |
author_facet | Hassan, Muzamil Olamide Balogun, Rasheed Abiodun |
author_sort | Hassan, Muzamil Olamide |
collection | PubMed |
description | Racial disparities in incidence and outcomes of acute kidney injury (AKI) are pervasive and are driven in part by social inequities and other factors. It is well-documented that Black patients face higher risk of AKI and seemingly have a survival advantage compared to White counterparts. Various explanations have been advanced and suggested to account for this, including differences in susceptibility to kidney injury, severity of illness, and socioeconomic factors. In this review, we try to understand and further explore the link between race and AKI using the incidence, diagnosis, and management of AKI to illustrate how race is directly related to AKI outcomes, with a focus on Black and White individuals with AKI. In particular, we explore the effect of race-adjusted estimated glomerular filtration rate (eGFR) equation on AKI prediction and discuss racial disparities in the management of AKI and how this might contribute to racial differences in AKI-related mortality among Blacks with AKI. We also identify some opportunities for future research and advocacy. |
format | Online Article Text |
id | pubmed-9573379 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95733792022-10-17 The Effects of Race on Acute Kidney Injury Hassan, Muzamil Olamide Balogun, Rasheed Abiodun J Clin Med Review Racial disparities in incidence and outcomes of acute kidney injury (AKI) are pervasive and are driven in part by social inequities and other factors. It is well-documented that Black patients face higher risk of AKI and seemingly have a survival advantage compared to White counterparts. Various explanations have been advanced and suggested to account for this, including differences in susceptibility to kidney injury, severity of illness, and socioeconomic factors. In this review, we try to understand and further explore the link between race and AKI using the incidence, diagnosis, and management of AKI to illustrate how race is directly related to AKI outcomes, with a focus on Black and White individuals with AKI. In particular, we explore the effect of race-adjusted estimated glomerular filtration rate (eGFR) equation on AKI prediction and discuss racial disparities in the management of AKI and how this might contribute to racial differences in AKI-related mortality among Blacks with AKI. We also identify some opportunities for future research and advocacy. MDPI 2022-09-30 /pmc/articles/PMC9573379/ /pubmed/36233687 http://dx.doi.org/10.3390/jcm11195822 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Hassan, Muzamil Olamide Balogun, Rasheed Abiodun The Effects of Race on Acute Kidney Injury |
title | The Effects of Race on Acute Kidney Injury |
title_full | The Effects of Race on Acute Kidney Injury |
title_fullStr | The Effects of Race on Acute Kidney Injury |
title_full_unstemmed | The Effects of Race on Acute Kidney Injury |
title_short | The Effects of Race on Acute Kidney Injury |
title_sort | effects of race on acute kidney injury |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573379/ https://www.ncbi.nlm.nih.gov/pubmed/36233687 http://dx.doi.org/10.3390/jcm11195822 |
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