Cargando…

Association of Urinary Iodine Concentration with Depressive Symptoms among Adults: NHANES 2007–2018

The association between iodine status and depressive symptoms has not been investigated in the general population. Therefore, we drew 8935 participants from the National Health and Nutrition Examination Survey (NHANES) 2007–2018 to explore their association. In NHANES, Inductively Coupled Plasma Dyn...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Shumin, Cui, Kaiwen, Luo, Jia, Zhang, Dongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573473/
https://www.ncbi.nlm.nih.gov/pubmed/36235816
http://dx.doi.org/10.3390/nu14194165
_version_ 1784810879240372224
author Chen, Shumin
Cui, Kaiwen
Luo, Jia
Zhang, Dongfeng
author_facet Chen, Shumin
Cui, Kaiwen
Luo, Jia
Zhang, Dongfeng
author_sort Chen, Shumin
collection PubMed
description The association between iodine status and depressive symptoms has not been investigated in the general population. Therefore, we drew 8935 participants from the National Health and Nutrition Examination Survey (NHANES) 2007–2018 to explore their association. In NHANES, Inductively Coupled Plasma Dynamic Reaction Cell Mass Spectroscopy was utilized to measure urinary iodine concentration (UIC), and Patient Health Questionnaire-9 was used to assess depressive symptoms. Meanwhile, we fitted logistic regression and restricted cubic spline models. We found that high UIC was associated with a higher prevalence of depressive symptoms than the normal UIC group (OR: 1.50, 95% CI: 1.04–2.16). This association was particularly pronounced and further strengthened among females (OR: 1.90, 95% CI: 1.19–3.01) and participants aged 40–59 (OR: 1.90, 95% CI: 1.11–3.25). Moreover, we found that low UIC was associated with a high prevalence of depressive symptoms among females (OR: 1.50, 95% CI: 1.02–2.18). Moreover, the dose-response relationship between UIC and depressive symptoms presented a general trend of decreased, steady transiently, and then increased. We found that participants with high UIC had a higher prevalence of depressive symptoms than those with normal UIC. Meanwhile, we also found that females with low UIC had higher odds of reporting depressive symptoms.
format Online
Article
Text
id pubmed-9573473
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-95734732022-10-17 Association of Urinary Iodine Concentration with Depressive Symptoms among Adults: NHANES 2007–2018 Chen, Shumin Cui, Kaiwen Luo, Jia Zhang, Dongfeng Nutrients Article The association between iodine status and depressive symptoms has not been investigated in the general population. Therefore, we drew 8935 participants from the National Health and Nutrition Examination Survey (NHANES) 2007–2018 to explore their association. In NHANES, Inductively Coupled Plasma Dynamic Reaction Cell Mass Spectroscopy was utilized to measure urinary iodine concentration (UIC), and Patient Health Questionnaire-9 was used to assess depressive symptoms. Meanwhile, we fitted logistic regression and restricted cubic spline models. We found that high UIC was associated with a higher prevalence of depressive symptoms than the normal UIC group (OR: 1.50, 95% CI: 1.04–2.16). This association was particularly pronounced and further strengthened among females (OR: 1.90, 95% CI: 1.19–3.01) and participants aged 40–59 (OR: 1.90, 95% CI: 1.11–3.25). Moreover, we found that low UIC was associated with a high prevalence of depressive symptoms among females (OR: 1.50, 95% CI: 1.02–2.18). Moreover, the dose-response relationship between UIC and depressive symptoms presented a general trend of decreased, steady transiently, and then increased. We found that participants with high UIC had a higher prevalence of depressive symptoms than those with normal UIC. Meanwhile, we also found that females with low UIC had higher odds of reporting depressive symptoms. MDPI 2022-10-07 /pmc/articles/PMC9573473/ /pubmed/36235816 http://dx.doi.org/10.3390/nu14194165 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chen, Shumin
Cui, Kaiwen
Luo, Jia
Zhang, Dongfeng
Association of Urinary Iodine Concentration with Depressive Symptoms among Adults: NHANES 2007–2018
title Association of Urinary Iodine Concentration with Depressive Symptoms among Adults: NHANES 2007–2018
title_full Association of Urinary Iodine Concentration with Depressive Symptoms among Adults: NHANES 2007–2018
title_fullStr Association of Urinary Iodine Concentration with Depressive Symptoms among Adults: NHANES 2007–2018
title_full_unstemmed Association of Urinary Iodine Concentration with Depressive Symptoms among Adults: NHANES 2007–2018
title_short Association of Urinary Iodine Concentration with Depressive Symptoms among Adults: NHANES 2007–2018
title_sort association of urinary iodine concentration with depressive symptoms among adults: nhanes 2007–2018
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573473/
https://www.ncbi.nlm.nih.gov/pubmed/36235816
http://dx.doi.org/10.3390/nu14194165
work_keys_str_mv AT chenshumin associationofurinaryiodineconcentrationwithdepressivesymptomsamongadultsnhanes20072018
AT cuikaiwen associationofurinaryiodineconcentrationwithdepressivesymptomsamongadultsnhanes20072018
AT luojia associationofurinaryiodineconcentrationwithdepressivesymptomsamongadultsnhanes20072018
AT zhangdongfeng associationofurinaryiodineconcentrationwithdepressivesymptomsamongadultsnhanes20072018