A Novel Utilization of Water Extract of Suaeda Salsa in the Pd/C Catalyzed Suzuki–Miyaura Coupling Reaction

Using biomass-derived solvents in various organic reactions is challenging for the fine chemicals industry. We herein report a Pd/C catalyzed Suzuki–Miyaura reaction in water extract of suaeda salsa (WES) without using external phosphine ligand, base, and organic solvent. The cross-coupling reaction...

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Autores principales: Ren, Changyue, Zhang, Hang, Chen, Zhengjun, Gao, Jie, Yang, Mingyan, Yuan, Zeli, Li, Xinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573658/
https://www.ncbi.nlm.nih.gov/pubmed/36235160
http://dx.doi.org/10.3390/molecules27196623
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author Ren, Changyue
Zhang, Hang
Chen, Zhengjun
Gao, Jie
Yang, Mingyan
Yuan, Zeli
Li, Xinmin
author_facet Ren, Changyue
Zhang, Hang
Chen, Zhengjun
Gao, Jie
Yang, Mingyan
Yuan, Zeli
Li, Xinmin
author_sort Ren, Changyue
collection PubMed
description Using biomass-derived solvents in various organic reactions is challenging for the fine chemicals industry. We herein report a Pd/C catalyzed Suzuki–Miyaura reaction in water extract of suaeda salsa (WES) without using external phosphine ligand, base, and organic solvent. The cross-coupling reactions were carried out in a basic WES medium with a broad substrate scope and wide functional group tolerance. Furthermore, the high purity of solid biaryl products can be obtained by column chromatography or filtration.
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spelling pubmed-95736582022-10-17 A Novel Utilization of Water Extract of Suaeda Salsa in the Pd/C Catalyzed Suzuki–Miyaura Coupling Reaction Ren, Changyue Zhang, Hang Chen, Zhengjun Gao, Jie Yang, Mingyan Yuan, Zeli Li, Xinmin Molecules Article Using biomass-derived solvents in various organic reactions is challenging for the fine chemicals industry. We herein report a Pd/C catalyzed Suzuki–Miyaura reaction in water extract of suaeda salsa (WES) without using external phosphine ligand, base, and organic solvent. The cross-coupling reactions were carried out in a basic WES medium with a broad substrate scope and wide functional group tolerance. Furthermore, the high purity of solid biaryl products can be obtained by column chromatography or filtration. MDPI 2022-10-06 /pmc/articles/PMC9573658/ /pubmed/36235160 http://dx.doi.org/10.3390/molecules27196623 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ren, Changyue
Zhang, Hang
Chen, Zhengjun
Gao, Jie
Yang, Mingyan
Yuan, Zeli
Li, Xinmin
A Novel Utilization of Water Extract of Suaeda Salsa in the Pd/C Catalyzed Suzuki–Miyaura Coupling Reaction
title A Novel Utilization of Water Extract of Suaeda Salsa in the Pd/C Catalyzed Suzuki–Miyaura Coupling Reaction
title_full A Novel Utilization of Water Extract of Suaeda Salsa in the Pd/C Catalyzed Suzuki–Miyaura Coupling Reaction
title_fullStr A Novel Utilization of Water Extract of Suaeda Salsa in the Pd/C Catalyzed Suzuki–Miyaura Coupling Reaction
title_full_unstemmed A Novel Utilization of Water Extract of Suaeda Salsa in the Pd/C Catalyzed Suzuki–Miyaura Coupling Reaction
title_short A Novel Utilization of Water Extract of Suaeda Salsa in the Pd/C Catalyzed Suzuki–Miyaura Coupling Reaction
title_sort novel utilization of water extract of suaeda salsa in the pd/c catalyzed suzuki–miyaura coupling reaction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573658/
https://www.ncbi.nlm.nih.gov/pubmed/36235160
http://dx.doi.org/10.3390/molecules27196623
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