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Structural Insight of KSIII (β-Ketoacyl-ACP Synthase)-like Acyltransferase ChlB3 in the Biosynthesis of Chlorothricin

Chlorothricin (CHL) belongs to a spirotetronate antibiotic family produced by Streptomyces antibioticus that inhibits pyruvate carboxylase and malate dehydrogenase. For the biosynthesis of CHL, ChlB3 plays a crucial role by introducing the 6-methylsalicylic acid (6MSA) moiety to ChlB2, an acyl carri...

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Detalles Bibliográficos
Autores principales:	Saeed, Asad Ullah, Rahman, Mueed Ur, Chen, Hai-Feng, Zheng, Jianting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573744/ https://www.ncbi.nlm.nih.gov/pubmed/36234941 http://dx.doi.org/10.3390/molecules27196405

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