Case Reports of Heroin Injection Site Necrosis: A Novel Antecedent of Nicolau Syndrome

Heroin injection-site necrosis (HISN) is a novel and poorly understood complication of intravenous drug abuse (IVDA). We present three cases of HISN that were evaluated and treated in Charleston, West Virginia, in 2019 and 2020. The documented cases show similarities involving patient care, follow-u...

Descripción completa

Detalles Bibliográficos
Autores principales: Rose, Brandon, Powell, Thomas G, Jones, Michelle, Chillag, Shawn A, Kemper, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Dermatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573776/
https://www.ncbi.nlm.nih.gov/pubmed/36258944
http://dx.doi.org/10.7759/cureus.29235
_version_ 1784810956627378176
author Rose, Brandon
Powell, Thomas G
Jones, Michelle
Chillag, Shawn A
Kemper, Suzanne
author_facet Rose, Brandon
Powell, Thomas G
Jones, Michelle
Chillag, Shawn A
Kemper, Suzanne
author_sort Rose, Brandon
collection PubMed
description Heroin injection-site necrosis (HISN) is a novel and poorly understood complication of intravenous drug abuse (IVDA). We present three cases of HISN that were evaluated and treated in Charleston, West Virginia, in 2019 and 2020. The documented cases show similarities involving patient care, follow-up, clinical progression, patient demographic, and dermatologic sequelae. We discuss these similarities, provide clinical recommendations, review proposed etiologies of HISN, and introduce Nicolau syndrome as a potential mechanism.
format Online
Article
Text
id pubmed-9573776
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-95737762022-10-17 Case Reports of Heroin Injection Site Necrosis: A Novel Antecedent of Nicolau Syndrome Rose, Brandon Powell, Thomas G Jones, Michelle Chillag, Shawn A Kemper, Suzanne Cureus Dermatology Heroin injection-site necrosis (HISN) is a novel and poorly understood complication of intravenous drug abuse (IVDA). We present three cases of HISN that were evaluated and treated in Charleston, West Virginia, in 2019 and 2020. The documented cases show similarities involving patient care, follow-up, clinical progression, patient demographic, and dermatologic sequelae. We discuss these similarities, provide clinical recommendations, review proposed etiologies of HISN, and introduce Nicolau syndrome as a potential mechanism. Cureus 2022-09-16 /pmc/articles/PMC9573776/ /pubmed/36258944 http://dx.doi.org/10.7759/cureus.29235 Text en Copyright © 2022, Rose et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Rose, Brandon
Powell, Thomas G
Jones, Michelle
Chillag, Shawn A
Kemper, Suzanne
Case Reports of Heroin Injection Site Necrosis: A Novel Antecedent of Nicolau Syndrome
title Case Reports of Heroin Injection Site Necrosis: A Novel Antecedent of Nicolau Syndrome
title_full Case Reports of Heroin Injection Site Necrosis: A Novel Antecedent of Nicolau Syndrome
title_fullStr Case Reports of Heroin Injection Site Necrosis: A Novel Antecedent of Nicolau Syndrome
title_full_unstemmed Case Reports of Heroin Injection Site Necrosis: A Novel Antecedent of Nicolau Syndrome
title_short Case Reports of Heroin Injection Site Necrosis: A Novel Antecedent of Nicolau Syndrome
title_sort case reports of heroin injection site necrosis: a novel antecedent of nicolau syndrome
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573776/
https://www.ncbi.nlm.nih.gov/pubmed/36258944
http://dx.doi.org/10.7759/cureus.29235
work_keys_str_mv AT rosebrandon casereportsofheroininjectionsitenecrosisanovelantecedentofnicolausyndrome
AT powellthomasg casereportsofheroininjectionsitenecrosisanovelantecedentofnicolausyndrome
AT jonesmichelle casereportsofheroininjectionsitenecrosisanovelantecedentofnicolausyndrome
AT chillagshawna casereportsofheroininjectionsitenecrosisanovelantecedentofnicolausyndrome
AT kempersuzanne casereportsofheroininjectionsitenecrosisanovelantecedentofnicolausyndrome

Ejemplares similares