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Overproduction, Purification, and Stability of the Functionally Active Human Carnitine Acetyl Transferase

Human Carnitine Acetyl Transferase (hCAT) reversibly catalyzes the transfer of the acetyl-moiety from acetyl-CoA to L-carnitine, modulating the acetyl-CoA/CoA ratio in mitochondria. Derangement of acetyl-CoA/CoA ratio leads to metabolic alterations that could result in the onset or worsening of path...

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Detalles Bibliográficos
Autores principales: Giudice, Deborah, Console, Lara, Arduini, Arduino, Indiveri, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573857/
https://www.ncbi.nlm.nih.gov/pubmed/35727434
http://dx.doi.org/10.1007/s12033-022-00522-z

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