Cargando…
Overproduction, Purification, and Stability of the Functionally Active Human Carnitine Acetyl Transferase
Human Carnitine Acetyl Transferase (hCAT) reversibly catalyzes the transfer of the acetyl-moiety from acetyl-CoA to L-carnitine, modulating the acetyl-CoA/CoA ratio in mitochondria. Derangement of acetyl-CoA/CoA ratio leads to metabolic alterations that could result in the onset or worsening of path...
Autores principales: | Giudice, Deborah, Console, Lara, Arduini, Arduino, Indiveri, Cesare |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573857/ https://www.ncbi.nlm.nih.gov/pubmed/35727434 http://dx.doi.org/10.1007/s12033-022-00522-z |
Ejemplares similares
-
The Mitochondrial Carnitine Acyl-carnitine Carrier (SLC25A20): Molecular Mechanisms of Transport, Role in Redox Sensing and Interaction with Drugs
por: Tonazzi, Annamaria, et al.
Publicado: (2021) -
Characterization of Exosomal SLC22A5 (OCTN2) carnitine transporter
por: Console, Lara, et al.
Publicado: (2018) -
Carnitine Traffic in Cells. Link With Cancer
por: Console, Lara, et al.
Publicado: (2020) -
Inhibition of the Mitochondrial Carnitine/Acylcarnitine Carrier by Itaconate through Irreversible Binding to Cysteine 136: Possible Pathophysiological Implications
por: Giangregorio, Nicola, et al.
Publicado: (2023) -
Cholesterol stimulates the cellular uptake of L-carnitine by the carnitine/organic cation transporter novel 2 (OCTN2)
por: Zhang, Lu, et al.
Publicado: (2021)