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HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia

Acute myeloid leukemia (AML) is maintained by self-renewing leukemic stem cells (LSCs). A fundamental problem in treating AML is that conventional therapy fails to eliminate LSCs, which can reinitiate leukemia. Heat shock transcription factor 1 (HSF1), a central regulator of the stress response, has...

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Detalles Bibliográficos
Autores principales:	Dong, Qianze, Xiu, Yan, Wang, Yang, Hodgson, Christina, Borcherding, Nick, Jordan, Craig, Buchanan, Jane, Taylor, Eric, Wagner, Brett, Leidinger, Mariah, Holman, Carol, Thiele, Dennis J., O’Brien, Sean, Xue, Hai-hui, Zhao, Jinming, Li, Qingchang, Meyerson, Howard, Boyce, Brendan F., Zhao, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573868/ https://www.ncbi.nlm.nih.gov/pubmed/36245043 http://dx.doi.org/10.1038/s41467-022-33861-1

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