Enhanced radiation-induced immunogenic cell death activates chimeric antigen receptor T cells by targeting CD39 against glioblastoma

Chimeric antigen receptor (CAR)-T cells directed to solid tumors have been less effective, due in part to the low or lost expression of specific tumor antigens. Herein, we developed a different strategy to enhance CAR-T cell persistence and efficacy by producing a multispecific CAR-T or vaccine base...

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Detalles Bibliográficos
Autores principales: Sun, Ting, Li, Yanyan, Yang, Ying, Liu, Bin, Cao, Yufei, Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573869/
https://www.ncbi.nlm.nih.gov/pubmed/36245000
http://dx.doi.org/10.1038/s41419-022-05319-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573869/
https://www.ncbi.nlm.nih.gov/pubmed/36245000
http://dx.doi.org/10.1038/s41419-022-05319-1

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