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Tristetraprolin limits age-related expansion of myeloid-derived suppressor cells

Aging results in enhanced myelopoiesis, which is associated with an increased prevalence of myeloid leukemias and the production of myeloid-derived suppressor cells (MDSCs). Tristetraprolin (TTP) is an RNA binding protein that regulates immune-related cytokines and chemokines by destabilizing target...

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Detalles Bibliográficos
Autores principales: Kwack, Kyu Hwan, Zhang, Lixia, Kramer, Elliot D., Thiyagarajan, Ramkumar, Lamb, Natalie A., Arao, Yukitomo, Bard, Jonathan E., Seldeen, Kenneth L., Troen, Bruce R., Blackshear, Perry J., Abrams, Scott I., Kirkwood, Keith L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573970/
https://www.ncbi.nlm.nih.gov/pubmed/36263047
http://dx.doi.org/10.3389/fimmu.2022.1002163