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Tristetraprolin limits age-related expansion of myeloid-derived suppressor cells
Aging results in enhanced myelopoiesis, which is associated with an increased prevalence of myeloid leukemias and the production of myeloid-derived suppressor cells (MDSCs). Tristetraprolin (TTP) is an RNA binding protein that regulates immune-related cytokines and chemokines by destabilizing target...
Autores principales: | Kwack, Kyu Hwan, Zhang, Lixia, Kramer, Elliot D., Thiyagarajan, Ramkumar, Lamb, Natalie A., Arao, Yukitomo, Bard, Jonathan E., Seldeen, Kenneth L., Troen, Bruce R., Blackshear, Perry J., Abrams, Scott I., Kirkwood, Keith L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573970/ https://www.ncbi.nlm.nih.gov/pubmed/36263047 http://dx.doi.org/10.3389/fimmu.2022.1002163 |
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