A physical perspective to understand myelin II: The physical origin of myelin development

The physical principle of myelin development is obtained from our previous study by explaining Peter’s quadrant mystery: an externally applied negative and positive E-field can promote and inhibit the growth of the inner tongue of the myelin sheath, respectively. In this study, this principle is con...

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Autores principales: Liu, Yonghong, Yue, Wenji, Yu, Shoujun, Zhou, Tian, Zhang, Yapeng, Zhu, Ran, Song, Bing, Guo, Tianruo, Liu, Fenglin, Huang, Yubin, Wu, Tianzhun, Wang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574017/
https://www.ncbi.nlm.nih.gov/pubmed/36263368
http://dx.doi.org/10.3389/fnins.2022.951998
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author Liu, Yonghong
Yue, Wenji
Yu, Shoujun
Zhou, Tian
Zhang, Yapeng
Zhu, Ran
Song, Bing
Guo, Tianruo
Liu, Fenglin
Huang, Yubin
Wu, Tianzhun
Wang, Hao
author_facet Liu, Yonghong
Yue, Wenji
Yu, Shoujun
Zhou, Tian
Zhang, Yapeng
Zhu, Ran
Song, Bing
Guo, Tianruo
Liu, Fenglin
Huang, Yubin
Wu, Tianzhun
Wang, Hao
author_sort Liu, Yonghong
collection PubMed
description The physical principle of myelin development is obtained from our previous study by explaining Peter’s quadrant mystery: an externally applied negative and positive E-field can promote and inhibit the growth of the inner tongue of the myelin sheath, respectively. In this study, this principle is considered as a fundamental hypothesis, named Hypothesis-E, to explain more phenomena about myelin development systematically. Specifically, the g-ratio and the fate of the Schwann cell’s differentiation are explained in terms of the E-field. Moreover, an experiment is proposed to validate this theory.
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spelling pubmed-95740172022-10-18 A physical perspective to understand myelin II: The physical origin of myelin development Liu, Yonghong Yue, Wenji Yu, Shoujun Zhou, Tian Zhang, Yapeng Zhu, Ran Song, Bing Guo, Tianruo Liu, Fenglin Huang, Yubin Wu, Tianzhun Wang, Hao Front Neurosci Neuroscience The physical principle of myelin development is obtained from our previous study by explaining Peter’s quadrant mystery: an externally applied negative and positive E-field can promote and inhibit the growth of the inner tongue of the myelin sheath, respectively. In this study, this principle is considered as a fundamental hypothesis, named Hypothesis-E, to explain more phenomena about myelin development systematically. Specifically, the g-ratio and the fate of the Schwann cell’s differentiation are explained in terms of the E-field. Moreover, an experiment is proposed to validate this theory. Frontiers Media S.A. 2022-10-03 /pmc/articles/PMC9574017/ /pubmed/36263368 http://dx.doi.org/10.3389/fnins.2022.951998 Text en Copyright © 2022 Liu, Yue, Yu, Zhou, Zhang, Zhu, Song, Guo, Liu, Huang, Wu and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Liu, Yonghong
Yue, Wenji
Yu, Shoujun
Zhou, Tian
Zhang, Yapeng
Zhu, Ran
Song, Bing
Guo, Tianruo
Liu, Fenglin
Huang, Yubin
Wu, Tianzhun
Wang, Hao
A physical perspective to understand myelin II: The physical origin of myelin development
title A physical perspective to understand myelin II: The physical origin of myelin development
title_full A physical perspective to understand myelin II: The physical origin of myelin development
title_fullStr A physical perspective to understand myelin II: The physical origin of myelin development
title_full_unstemmed A physical perspective to understand myelin II: The physical origin of myelin development
title_short A physical perspective to understand myelin II: The physical origin of myelin development
title_sort physical perspective to understand myelin ii: the physical origin of myelin development
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574017/
https://www.ncbi.nlm.nih.gov/pubmed/36263368
http://dx.doi.org/10.3389/fnins.2022.951998
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