The proneural transcription factor ASCL1 regulates cell proliferation and primes for differentiation in neuroblastoma

Neuroblastoma is believed to arise from sympathetic neuroblast precursors that fail to engage the neuronal differentiation programme, but instead become locked in a pro-proliferative developmental state. Achaete-scute homolog 1 (ASCL1) is a proneural master regulator of transcription which modulates...

Descripción completa

Detalles Bibliográficos
Autores principales: Parkinson, Lydia M., Gillen, Sarah L., Woods, Laura M., Chaytor, Lewis, Marcos, Daniel, Ali, Fahad R., Carroll, Jason S., Philpott, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574099/
https://www.ncbi.nlm.nih.gov/pubmed/36263020
http://dx.doi.org/10.3389/fcell.2022.942579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574099/
https://www.ncbi.nlm.nih.gov/pubmed/36263020
http://dx.doi.org/10.3389/fcell.2022.942579

Ejemplares similares