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Permanent tissue damage in multiple sclerosis lesions is associated with reduced pre-lesion myelin and axon volume fractions
BACKGROUND: The use of advanced magnetic resonance imaging (MRI) techniques in MS research has led to new insights in lesion evolution and disease outcomes. It has not yet been determined if, or how, pre-lesional abnormalities in normal-appearing white matter (NAWM) relate to the long-term evolution...
Autores principales: | Tagge, Ian J, Leppert, Ilana R, Fetco, Dumitru, Campbell, Jennifer SW, Rudko, David A, Brown, Robert A, Stikov, Nikola, Pike, G Bruce, Giacomini, Paul S, Arnold, Douglas L, Narayanan, Sridar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574230/ https://www.ncbi.nlm.nih.gov/pubmed/35903888 http://dx.doi.org/10.1177/13524585221110585 |
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