A Protumorigenic mDia2–MIRO1 Axis Controls Mitochondrial Positioning and Function in Cancer-Associated Fibroblasts

Cancer-associated fibroblasts (CAF) are key regulators of tumorigenesis. Further insights into the tumor-promoting mechanisms of action of CAFs could help improve cancer diagnosis and treatment. Here we show that the formin mDia2 regulates the positioning and function of mitochondria in dermal fibro...

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Detalles Bibliográficos
Autores principales: Cangkrama, Michael, Liu, Huan, Whipman, James, Zubair, Maria, Matsushita, Mai, Di Filippo, Michela, Kopf, Manfred, Innocenti, Metello, Werner, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Molecular Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574377/
https://www.ncbi.nlm.nih.gov/pubmed/35997559
http://dx.doi.org/10.1158/0008-5472.CAN-22-0162

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