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The significance of the first living donor kidney transplantation in Jeju: a case report

To overcome the shortage of kidney donors, diverse methods have been utilized, including living donor kidney transplantation (LDKT) and extended criteria for deceased donor grafts. Currently, LDKT is a major treatment option. However, in Jeju, deceased donor kidney transplantation (DDKT) has been re...

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Autores principales: Shin, Young-Heun, Lee, Taeseung, Chang, Won-Bae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Transplantation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574429/
https://www.ncbi.nlm.nih.gov/pubmed/36275993
http://dx.doi.org/10.4285/kjt.22.0033
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author Shin, Young-Heun
Lee, Taeseung
Chang, Won-Bae
author_facet Shin, Young-Heun
Lee, Taeseung
Chang, Won-Bae
author_sort Shin, Young-Heun
collection PubMed
description To overcome the shortage of kidney donors, diverse methods have been utilized, including living donor kidney transplantation (LDKT) and extended criteria for deceased donor grafts. Currently, LDKT is a major treatment option. However, in Jeju, deceased donor kidney transplantation (DDKT) has been restricted due to the prolonged cold ischemia time (CIT) caused by the island’s geographic disadvantages and transportation limitations. We report the first LDKT in Jeju, which demonstrates a means of overcoming prolonged CIT. A 67-year-old male patient with diabetic nephropathy underwent a preemptive ABO compatible LDKT (ABO type O+) from his 62-year-old wife. The operation was uneventful, using anti-thymocyte globulin based on the recipient’s medical and immunologic risks. The patient recovered without significant complications and was discharged on postoperative day 15. Follow-up Doppler ultrasonography showed good blood flow to the kidney, and his serum creatinine levels steadily decreased and remained stable. The first successful LDKT in Jeju was significant in that kidney transplantation was implemented by compensating for its geographic limitations. In addition, we review machine perfusion as another method of avoiding prolonged CIT.
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spelling pubmed-95744292022-10-21 The significance of the first living donor kidney transplantation in Jeju: a case report Shin, Young-Heun Lee, Taeseung Chang, Won-Bae Korean J Transplant Case Report To overcome the shortage of kidney donors, diverse methods have been utilized, including living donor kidney transplantation (LDKT) and extended criteria for deceased donor grafts. Currently, LDKT is a major treatment option. However, in Jeju, deceased donor kidney transplantation (DDKT) has been restricted due to the prolonged cold ischemia time (CIT) caused by the island’s geographic disadvantages and transportation limitations. We report the first LDKT in Jeju, which demonstrates a means of overcoming prolonged CIT. A 67-year-old male patient with diabetic nephropathy underwent a preemptive ABO compatible LDKT (ABO type O+) from his 62-year-old wife. The operation was uneventful, using anti-thymocyte globulin based on the recipient’s medical and immunologic risks. The patient recovered without significant complications and was discharged on postoperative day 15. Follow-up Doppler ultrasonography showed good blood flow to the kidney, and his serum creatinine levels steadily decreased and remained stable. The first successful LDKT in Jeju was significant in that kidney transplantation was implemented by compensating for its geographic limitations. In addition, we review machine perfusion as another method of avoiding prolonged CIT. The Korean Society for Transplantation 2022-09-30 2022-08-25 /pmc/articles/PMC9574429/ /pubmed/36275993 http://dx.doi.org/10.4285/kjt.22.0033 Text en Copyright © 2022 The Korean Society for Transplantation https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Shin, Young-Heun
Lee, Taeseung
Chang, Won-Bae
The significance of the first living donor kidney transplantation in Jeju: a case report
title The significance of the first living donor kidney transplantation in Jeju: a case report
title_full The significance of the first living donor kidney transplantation in Jeju: a case report
title_fullStr The significance of the first living donor kidney transplantation in Jeju: a case report
title_full_unstemmed The significance of the first living donor kidney transplantation in Jeju: a case report
title_short The significance of the first living donor kidney transplantation in Jeju: a case report
title_sort significance of the first living donor kidney transplantation in jeju: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574429/
https://www.ncbi.nlm.nih.gov/pubmed/36275993
http://dx.doi.org/10.4285/kjt.22.0033
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