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The atypical Rab GTPase associated with Parkinson’s disease, Rab29, is localized to membranes

Several genetic studies have shown that the small GTPase Rab29 is involved in the pathogenesis of Parkinson’s Disease (PD). It has also been shown that overexpression of Rab29 increases the activity of leucine-rich repeat kinase 2, a protein kinase often mutated in familial PD, although the mechanis...

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Detalles Bibliográficos
Autores principales: Nagai-Ito, Yuki, Xu, Lejia, Ito, Kyohei, Kajihara, Yotaro, Ito, Genta, Tomita, Taisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574512/
https://www.ncbi.nlm.nih.gov/pubmed/36116551
http://dx.doi.org/10.1016/j.jbc.2022.102499

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