A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability

The IL-3, IL-5, and GM-CSF family of cytokines play an essential role in the growth, differentiation, and effector functions of multiple hematopoietic cell types. Receptors in this family are composed of cytokine-specific α chains and a common β chain (CSF2RB), responsible for the majority of downst...

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Detalles Bibliográficos
Autores principales: Koochaki, Sebastian H.J., Słabicki, Mikołaj, Lumpkin, Ryan, Zou, Charles, Belizaire, Roger, Fischer, Eric S., Ebert, Benjamin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574515/
https://www.ncbi.nlm.nih.gov/pubmed/36108743
http://dx.doi.org/10.1016/j.jbc.2022.102484

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