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Impaired disassembly of the axon initial segment restricts mitochondrial entry into damaged axons

The proteasome is essential for cellular responses to various physiological stressors. However, how proteasome function impacts the stress resilience of regenerative damaged motor neurons remains unclear. Here, we develop a unique mouse model using a regulatory element of the activating transcriptio...

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Detalles Bibliográficos
Autores principales: Kiryu‐Seo, Sumiko, Matsushita, Reika, Tashiro, Yoshitaka, Yoshimura, Takeshi, Iguchi, Yohei, Katsuno, Masahisa, Takahashi, Ryosuke, Kiyama, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574747/
https://www.ncbi.nlm.nih.gov/pubmed/36004759
http://dx.doi.org/10.15252/embj.2021110486