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Impaired disassembly of the axon initial segment restricts mitochondrial entry into damaged axons
The proteasome is essential for cellular responses to various physiological stressors. However, how proteasome function impacts the stress resilience of regenerative damaged motor neurons remains unclear. Here, we develop a unique mouse model using a regulatory element of the activating transcriptio...
Autores principales: | Kiryu‐Seo, Sumiko, Matsushita, Reika, Tashiro, Yoshitaka, Yoshimura, Takeshi, Iguchi, Yohei, Katsuno, Masahisa, Takahashi, Ryosuke, Kiyama, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574747/ https://www.ncbi.nlm.nih.gov/pubmed/36004759 http://dx.doi.org/10.15252/embj.2021110486 |
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