An optimized method for purifying, detecting and quantifying Mycobacterium tuberculosis RNA from sputum for monitoring treatment response in TB patients

Diagnostics that more accurately detect and quantify viable Mycobacterium tuberculosis (Mtb) in the sputum of patients undergoing therapy are needed. Current culture- and molecular-based tests have shown limited efficacy for monitoring treatment response in TB patients, either due to the presence of...

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Detalles Bibliográficos
Autores principales: Zainabadi, Kayvan, Lee, Myung Hee, Walsh, Kathleen Frances, Vilbrun, Stalz Charles, Mathurin, Laurent Daniel, Ocheretina, Oksana, Pape, Jean William, Fitzgerald, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574834/
https://www.ncbi.nlm.nih.gov/pubmed/36253384
http://dx.doi.org/10.1038/s41598-022-19985-w

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