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Targeting the Phosphatidylserine-Immune Checkpoint with a Small-Molecule Maytansinoid Conjugate
[Image: see text] Ligand-targeting drug delivery systems have made significant strides for disease treatments with numerous clinical approvals in this era of precision medicine. Herein, we report a class of small molecule-based immune checkpoint-targeting maytansinoid conjugates. From the ligand tar...
Autores principales: | Lo, Chen-Fu, Chiu, Tai-Yu, Liu, Yu-Tzu, Pan, Pei-Yun, Liu, Kuan-Liang, Hsu, Chia-Yu, Fang, Ming-Yu, Huang, Yu-Chen, Yeh, Teng-Kuang, Hsu, Tsu-An, Chen, Chiung-Tong, Huang, Li-Rung, Tsou, Lun Kelvin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574934/ https://www.ncbi.nlm.nih.gov/pubmed/36153998 http://dx.doi.org/10.1021/acs.jmedchem.2c00631 |
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